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The OBELISK project, coordinated by Jana Selent, will receive funding from the Horizon Europe programme of the European Union
The Hospital del Mar Institute for Medical Research (IMIM- Hospital del Mar) will participate in four projects that will receive funding from the European Union's Horizon Europe programme. In total, around EUR 30 million will be earmarked for research in the fields of oncological surgery, oncology, obesity and mental health. Of these, almost 2.5 million will go directly to research carried out at the IMIM-Hospital del Mar.
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EMA selects Hospital del Mar Institute for Medical Research and Hospital de Mar to be data partner of the DARWIN EU data network®
The European Medicines Agency selected Hospital del Mar and the Hospital del Mar Medical Research Institute to be a Data Partner of the DARWIN EU® data network, an EU-wide federated network of high-quality observational healthcare databases across Europe, that provides expertise and services to support regulatory decision-making throughout the lifecycle of medicinal products.
FBBVA - Development of novel transcriptome-informed methods to predict the response to immunotherapy in cancer
The goal of this project is to use DNA and RNA sequencing data collected from hundreds of patients with advanced bladder cancer, including a cohort at Hospital del Mar in Barcelona, to develop predictive models of the response to immunotherapy. We expect that, by including different types of neoantigens and new molecular biomarkers in the models, we will be able to achieve higher accuracy in the predictive models. The project is undertaken by a highly multidisciplinary team led by Mar Albà. The funding is for the period 2022-2024.
- Rodríguez-Belenguer P, Kopańska K, Llopis-Lorente J, Trenor B, Saiz J, Pastor M. Application of machine learning to improve the efficiency of electrophysiological simulations used for the prediction of drug-induced ventricular arrhythmia. Comput Methods Programs Biomed, 2023; 230: 107345. PMID: 36689808 . DOI: 10.1016/j.cmpb.2023.107345.
- Juan D, Santpere G, Kelley JL et al. Current advances in primate genomics: novel approaches for understanding evolution and disease. Nat Rev Genet, 2023. PMID: 36599936 . DOI: 10.1038/s41576-022-00554-w.
- Matos-Filipe P, García-Illarramendi JM, Jorba G, Oliva B, Farrés J, Mas JM. The usage of transcriptomics datasets as sources of Real-World Data for clinical trialling. bioRxiv, 2022 DOI: 10.1101/2022.11.10.515995.
- Fernández-Ginés R, Encinar JA, Hayes JD, Oliva B, Rodríguez-Franco MI, Rojo AI, Cuadrado A. An inhibitor of interaction between the transcription factor NRF2 and the E3 ubiquitin ligase adapter β-TrCP delivers anti-inflammatory responses in mouse liver. Redox Biol. 2022 Jul 11;55:102396. PMID: 35839629 . DOI: 10.1016/j.redox.2022.102396.
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