GRIB. Research Unit on Biomedical Informatics





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GRIB participates in the Disc4All Project, an innovative training network of the European Commission

Ferran Sanz, Laura I. Furlong and Baldo Oliva will participate in the Disc4All project: Training network to advance integrated computational simulations in translational medicine, applied to intervertebral disc degeneration, coordinated by Jérôme Noailly, principal investigator in the Biomechanics and Mechanobiology research area at BCN MedTech of UPF. It is one of the ten selected projects in Catalonia as an Innovative Training Network (ITN) Marie Sklodowska-Curie, in the European Commission's ITN MSC Actions call.

The European innovative training networks (ITN) aim to train a new generation of researchers in their early stages who are creative, enterprising and innovative, capable of dealing with the challenges of the future and turn knowledge and ideas into products and services with an economic and a social benefit. ITN programmes within the framework of the European Commission's Marie Sklodowska-Curie Actions support joint competitive programmes for training in research or joint doctorates. These programmes will be implemented by partnerships of universities, research centres, businesses, SMEs and other stakeholders in Europe and the rest of the world.

As part of this project, the GRIB will train young researchers in the tools available to analyze genomic data (DisGeNET) and comorbidities (comoRbidity). DisGeNET is a public knowledge management platform that offers information on genes and genomic variants associated with human diseases, which is obtained by integrating data from more than a dozen public resources and the scientific literature It contains one of the most comprehensive collections of genes and variants associated with human diseases that is currently available. On the other hand comoRbidity, is a program designed to provide a systematic and complete analysis of the comorbidities of the disease from both a clinical and molecular perspective.

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The version 7.0 of DisGeNET is now available and includes the creation of a new resource for COVID-19

The GRIB Integrative Biomedical Informatics group (IMIM-UPF) has launched a new version of DisGeNET (version 7.0, May 8, 2020), which contains more than 1 million associations between 21,000 genes and 30,000 diseases, and 350,000 associations involving more than 190,000 genomic variants. All the data sources have been updated including the information automatically extracted by text mining of the literature. In addition, a new resource focused on COVID-19 has also been created.

DisGeNET is a public knowledge management platform that offers information on genes and genomic variants associated with human diseases, which is obtained by integrating data from more than a dozen public resources and the scientific literature. DisGeNET contains one of the most comprehensive collections of genes and variants associated with human diseases that is currently available and is a resource for sharing and exchanging information recommended by the ELIXIR project, which is called, ELIXIR Recommended Interoperability Resource.

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Disc4All

Disc4All Project, an innovative training network funded by the European Commission for the period 2020 - 2023, aims to integrate available data and computational simulations on back pain caused by intervertebral disc degeneration with a multidisciplinary translational medicine approach.   

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