The chronic lymphocytic leukaemia project reveals the first oncogenic mutations

The International Cancer Genome Consortium, which will study the genomes of more than 25,000 cancer patients, has presented its latest research results in the journal Nature

The chronic lymphocytic leukemia genome project is coordinated in Spain, and the researcher Nuria López-Bigas, head of Biomedical Genomics laboratory of GRIB (IMIM-UPF) participates on the bioinformatics analysis of data and the coordination and management of Consortium data.

The project is funded by the Ministry of Science and Innovation, with the participation of a multidisciplinary team of researchers from the Hospital Clinic of Barcelona, the University of Barcelona, the University of Oviedo, the Center for Genomic Regulation in Barcelona, the Catalan Institute of Oncology, the Spanish National Cancer Research Center, the Cancer Research Center of Salamanca, the University of Deusto and the University Pompeu Fabra. With the creation of the new National Center for Genomic Analysis (CNAG) in Barcelona, the bulk of the sequence data will be produced at this center, while the analysis and validation of the information generated will be directed by the University of Oviedo (Carlos López-Otín), the Hospital Clinic of Barcelona (Elías Campo), and the Center for Genomic Regulation (Xavier Estivill and Roderic Guigó).

Reference work: The International Cancer Genome Consortium (2010). "International network of cancer genome projects". Nature. DOI: 10.1038/nature08987

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