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• genetic risk indicator has been developed that is associated with the probability of ischaemic heart disease

  31/08/2010 - Press release

  A study led by IMIM researchers in Barcelona has developed a genetic risk indicator that has a linear association with the probability of ischaemic heart disease. This risk indicator is independent of classic cardiovascular risk factors already known and may provide information that is supplementary to them.

• Cigarette smoke contributes to muscle dysfunction

  10 august 2010 - Press release

  This is the first study in which proteins involved in metabolism and muscle contraction are shown to have higher levels of oxidation as a result of tobacco smoke, which could cause alterations in the structure and function of muscle fibres.

• 59 new genetic variants associated with blood cholesterol and triglyceride levels have been identified

  4th august 2010 - Press release

  An international study which will be published in the next issue of the prestigious journal Nature, in which researchers from the IMIM have participated, has identified 95 genetic variants related to LDL cholesterol, HDL cholesterol and triglyceride levels. Of these 95 associated genetic variants, 59 had not been previously identified.

• A new antibody-producing molecular mechanism has been identified which could be key to lupus or rheumatoid arthritis

  1 august 2010 - Press release

  An international team, led by the IMIM (Hospital del Mar Research Institute) and the Mount Sinai School of Medicine in New York, has identified a new molecular mechanism for the production of antibodies by B-lymphocytes. This finding opens the door to new treatments for autoimmune diseases, such as lupus and rheumatoid arthritis, and perhaps tumors of the immune system such as lymphoma and multiple myeloma.

• Rare genetic variants also contribute to the appearance of complex diseases

  22 july 2010 - Press release

  An international study, in which researchers from the IMIM (Hospital del Mar Research Institute) have participated as the only Spanish researchers, has shown that rare genetic variants, which are present in less than 1% of the population, also contribute to determining individual susceptibility to suffer from complex diseases such as hypertriglyceridemia (high levels of triglycerides).

• 20th European Athletics Championships

  12/07/2010 - General information

  The City of Barcelona will host from 27 July to 1 August 2010 the 20th European Athletics Championships, Barcelona 2010. The Hospital del Mar will be one of the reference hospitals for both its timetabled care (tests) as well as emergency services and the IMIM's Anti-Doping Control Laboratory will be in charge of performing the doping control tests for the championships

• Kidney disease in patients with heart-related chest pain increases the mortality risk

  07/07/2010 - General information

  According to an international study which IMIM took part, kidney disease is a significant predictor of in-hospital mortality and 30-day mortality in patients who come to the hospital with heart-related chest pain, otherwise known as Non-ST-segment Elevation Acute Coronary Syndrome (NSTE-ACS).

• Comparison of the human genome with genomes of other animals helps to identify new functional repetitive structures in proteins

  02/06/2010 - Press release

  A project executed by the research group on Evolutionary Genomics of GRIB (IMIM -UPF) employed comparison of the human genome with the genomes of other species of vertebrates to verify that the repetitive motifs found in human proteins are important for the good operation of the body and which could correspond to the fraction of the genome called ‘junk’ (with no function).

• Commercial release of Pentacle, an advanced tool for 3D QSAR and Virtual screening developed at GRIB

  28/05/2010 - General information

  Molecular Discovery Ltd, one of the world leader companies in chemoinformatics and services for the pharmaceutical industry has launched to the market the software Pentacle, developed at the Computer of Assisted Drug Design (CADD) laboratory by Ángel Durán and Manuel Pastor.

• The chronic lymphocytic leukaemia project reveals the first oncogenic mutations

  16/04/2010 - Events

  The International Cancer Genome Consortium, which will study the genomes of more than 25,000 cancer patients, has presented its latest research results in the journal Nature. The chronic lymphocytic leukemia genome project is coordinated in Spain, and the researcher Nuria López-Bigas, head of Biomedical Genomics laboratory of GRIB (IMIM-UPF) participates on the bioinformatics analysis of data and the coordination and management of Consortium data.