Tools




news

RSS

23/4/2014

Bioinformatics Barcelona ja aplega més de 40 entitats entre universitats, centres de recerca i empreses

La plataforma Bioinformatics Barcelona (BIB) va presentar ahir, 22 d'abril, el seu Pla Estratègic, en un acte presidit per Antoni Castellà, secretari d’Universitats i Recerca, a CaixaForum Barcelona. El BIB té el suport de 44 entitats del sistema de recerca i industrial català, entre les quals estan l’IMIM i la UPF.

El Pla Estratègic defineix línies d’acció ens els àmbits de la visibilitat, la formació, la col·laboració interna i externa, i la recerca i transferència, com a prioritats estratègiques. Aquest pla concreta les accions a fer en els propers anys i és el resultat del procés de consulta i diàleg portat a terme amb tots els sectors implicats en el camp de la bioinformàtica, entesa com a l’aplicació de les ciències computacionals per al tractament de dades biològiques.

El BIB està presidit per Ana Ripoll, ex rectora de la UAB, i compta amb la direcció científica de Ferran Sanz, director del programa de Recerca en Informàtica Biomèdica, GRIB (UPF-IMIM). La Generalitat de Catalunya i l’Obra Social “la Caixa” donen suport a aquesta nova iniciativa.

More information

Fragus

10/4/2014

Recents avenços per a l'estudi de les proteïnes i les seves interaccions

El grup de recerca en Bioinformàtica Estructural del GRIB (IMIM-UPF) que lidera Baldo Oliva ha presentat dos servidors web que facilitaran l'estudi de les configuracions de proteïnes i l'expressió de gens que intervenen en la manifestació de diverses malalties.

Un dels servidors desenvolupats pel grup de recerca  en Bioinformàtica Estructural s'anomena FRAGRUS i està adreçat al disseny de proteïnes. Aquest treball publicat a Bioinformatics s'ha fet en col·laboració amb Narcís Fernández-Fuentes, cap de grup de Bioinformàtica a la Universitat de Aberystwyth (Regne Unit), investigador que està fent una estada de recerca de dos anys al GRIB gràcies a un ajut TecnioSpring d'ACC10.

L'altre servidor web desenvolupat es el GUILDify per a la caracterització fenotípica de gens.Com ha manifestat Baldo Oliva: "l'estudi de les interaccions físiques entre proteïnes codificades per gens implicats en malalties específiques ha permès fer servir el principi de "culpabilitat per associació" per tal de predir aquestes noves dianes"

More information

New article of IBI group at Nature Reviews Drug Discovery

Information technologies already have a key role in pharmaceutical research but achieving substantial advances in their use and effectiveness will depend on overcoming current challenges in sharing, integrating and jointly analyzing the range of data generated at different stages of the R&D process. These challenges are related to the complexity and heterogeneity of biomedical data, the need to establish relevant, widely accepted and openly available data standards and the lack of integration of knowledge from different disciplines and stages of the R&D process. Overcoming these challenges was the subject of a debate in Brussels on July 2013 with the participation of experts and stakeholders led by Ferran Sanz, Director of the Research Programme on Biomedical Informatics.

The key points of the debate have been collected in the article Integrative knowledge management to enhance pharmaceutical R&D published in the prestigious Nature Reviews Drug Discovery. In the article, some initiatives to overcome these problems are discussed, which will be key for establishing knowledge management strategies in pharmaceutical R&D that efficiently exploit the increasing availability of novel biomedical data and learn from previous experience, thus enabling a more efficient search for innovative, effective and safe medicines.

More information

Open PHACTS project extension approved until 2016

An extension proposal (ENSO) of the EU-funded Open PHACTS project (www.openphacts.org) has been very positively evaluated by a panel of independent experts and has been approved by the IMI Government Board for receiving aditional funding. The strong consensus of the reviewers is that Open PHACTS is a well-run and successful collaborative project that deserves further support. The planned extension program of 18 months (until 2016) will address several new areas including new use cases: (i) target validation and hypothesis generation, (ii) personalised healthcare and (iii) use cases across IMI projects. These new areas are fully supported and are seen to add considerable extra value to the project.

GRIB participates in the Open PHACTS project as coordinator of one of the workpackages.

More information

11/3/2014

Compartir los datos para predecir mejor la toxicidad (Diario Médico, 10/3/2014)

El proyecto europeo e-TOX, coordinado por Ferran Sanz, director del GRIB, busca nuevos modelos predictivos del perfil toxicológico de las moléculas en investigación.

La toxicidad es uno de los problemas más frecuentes y temidos que aparecen en el transcurso de la I+D de nuevos medicamentos. Es una de las principales causas de fracaso de muchos estudios y uno de los principales responsables de que algunos candidatos a nuevos fármacos acaben en la papelera. Es por ello que la posibilidad de predecir de manera más precisa la toxicidad de determinadas moléculas resulte un objetivo importante para optimizar la investigación........ (leer artículo completo)

More information

Peter Cho (HTC CEO), G de Fabritiis (GRIB) and Cher Wang (HTC President) at MWC press conference

25/02/2014

Gianni de Fabritiis at the launch of "HTC Power to Give", a new mobile based volunteer computing project

As part of the Mobile World Congress, on February 24th, Taiwanese smartphone company HTC launched, before 200 journalists from around the world, the new project HTC Power to Give. The Power to Give application can be downloaded from Android phones allows to harness the processing capacity of smartphones for scientific purposes.

Gianni De Fabritiis, head of the Computational Biophysics group of GRIB (IMIM -UPF), was the only scientist invited to the event and shared stage with the president of HTC, Cher Wang and company CEO Peter Cho.

De Fabritiis participation consisted in explaining volunteer distributed computing and its importance in research. He spoke about his GPUGRID project created 7 years ago in which volunteer distributed computing is used for molecular dynamics simulations in biomedicine. Researchers computationally simulate how certain proteins responsible of diseases such as cancer , HIV etc. interact in order to see their behavior.

According to De Fabritiis "Such simulations require much computing power. In our early days we used the computing power of game consoles, then of graphic cards and now the mobile phones are the future ". HTC opens the door for smartphone owners; voluntary participation in the advancement of science in an easy, no-cost way. Gianni De Fabritiis' group has already developed an application for Power To Give that will soon be available for Android.

More information

VII Conferencia Anual de las Plataformas Tecnológicas de Investigación Biomédica en Barcelona

Los próximos días 4 y 5 de marzo se celebrará en el hotel FIRA PALACE de Barcelona la VII Conferencia Anual de las Plataformas Tecnológicas de Investigación Biomédica: Medicamentos Innovadores, Nanomedicina, Tecnología Sanitaria y Mercados Biotecnológicos. El Reto en Salud.

Esta séptima edición repasará las actividades de las cuatro plataformas de investigación biomédica en 2013 y debatirá aspectos clave que marcarán los proyectos para los próximos años, además de animar la participación española en diferentes iniciativas internacionales. 

Las inscripciones pueden realizarse vía web en: www.medicamentos-innovadores.org

El GRIB coordina junto a Farmaindustria la Plataforma Española de Medicamentos Innovadores (PTEMI) coorganizadora de este evento.

More information

29/01/2014

Animation on orphan genes

Jose Luis Villanueva and Mar Albà, members of the Evolutionary Genomics Group of GRIB (IMIM - UPF) have participated in the production of a video on orphan genes. The video explains the origin of genes, which are the main functional units in genomes. Whereas many genes are formed by duplication of preexisting genes others arise directly from genomic regions by still poorly understood mechanisms. The latter genes are called orphan genes and represent radically new inventions. The animation was produced during the 2013 edition of the Workshop Inform.animation at University of Alghero (Italy), funded by the EU Erasmus Lifelong Learning Programme. It was inspired in the work developed at the Evolutionary Genomics Group of GRIB, and in other groups around the world, on the birth of new genes.

More information

Ignasi Buch, Premi extraordinari de doctorat del curs 2011-12 a la UPF

La Comissió de Postgrau i Doctorat de la Universitat Pompeu Fabra ha decidit atorgar el premi extraordinari de doctorat del curs 2011-12 a l’estudiant Ignasi Buch per la tesi "Investigation of protein-ligand interactions using high-throughput all-atom molecular dynamics simulations" dirigida per Gianni de Fabritiis, cap del grup de Biofísica computacional del GRIB. Felicitats Ignasi!!!

More information

10/01/2014

Mar Albà has been nominated Associate Editor of Genome Biology and Evolution (GBE)

Mar Albà, ICREA researcher and head of the Evolutionary Genomics group of GRIB (IMIM-UPF), will serve a three-year term in the Editorial Board of Genome Biology and Evolution (GBE). GBE publishes leading original research at the interface between evolutionary biology and genomics. The journal was created five years ago by the Society for Molecular Biology and Evolution (SMBE) under an Open Access model and it is positioned to set the highest standards for papers in the growing field of evolutionary genomics. It is currently 10th out of 47 journals in evolutionary biology according to ISI.

More information



Site Information