“Ajudarem a millorar el diagnòstic i tractament de malalties”

Llegeix l'entrevista a Ferran Sanz, Director del GRIB, al ESCI news de la UPF, on ens explica DisGeNET, una base de dades que lliga gens amb malalties i quina relació hi ha entre DisGeNET i l'empresa que ha llençat amb un grup de científics, MedBioinformatics Solutions, per ajudar empreses del sector sanitari en el desenvolupament de tractaments adaptats a la genètica de cada pacient.

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Congratulations to Miguel-Angel Mayer for his appointment as a member of the Council for International Organizations of Medical Sciences Expert Working Group

Miguel-Angel Mayer, member of IBI group of the GRIB, has been invited to join the Council for International Organizations of Medical Sciences (CIOMS) XIII Expert Working Group. CIOMS is an international, non-governmental, non-profit organization established jointly by the World Health Organisation and UNESCO in 1949. CIOMS mission is to advance public health through guidance on health research including ethics, medical product development and safety. There is increasing interest in the use of Real-World data (RWD) to support regulatory decision making across products life cycle. Electronic health records, claims data, prescription data, and patient registries are some of the most important resources of RWD. Real-world evidence (RWE) is the clinical evidence about the usage and potential benefits or risks of a medical product derived from an analysis of RWD. CIOMS has proposed the development of a consensus report and recommendations for the use of RWD and RWE in regulatory decision-making related to biopharmaceutical products. Miguel-Angel Mayer said: "I am honoured to join CIOMS and work on this RWD/RWE consensus report and the opportunity to collaborate with the most important world experts in this field".

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Congratulations to Judith Pérez Granado for winning the Barcelona Science Slam

Last 22nd of February, the 7th Edition of the Barcelona Science Slam took place. For those who don't know, a science slam is a scientific communication contest where scientists explain their research projects in 5 minutes in an engaging, fun and clear way. PhD students and postdoctoral researchers are encouraged to join the experience and bring their research closer to the public. Judith Pérez Granado, PhD student at the Integrative Biomedical Informatics Group of GRIB, presented her PhD thesis project and was the winner of this Slam. She said: "To me, it was a pleasure to present my science in a fun and simple way so it could reach everyone. It made me even see my research from another perspective. To anyone that would like to participate, I would encourage him/her to do so. It is a great experience!"​. Here you are the video of the presentation.

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MedBioinformatics Solutions partners and researchers


The spin-off MedBioinformatics Solutions is to offer software and consultancy on relationships between genes and diseases

The company, founded today, is backed by IMIM and UPF and is developing products and services based on the DisGeNET platform, one of the tools on the genetics of diseases with most information in the world

The company came to life today, 6 February, with the signing of the deeds of incorporation by the acting director of IMIM, Jorge Martínez, the UPF general manager, Jaume Badia; the researchers and partners of the company, Ferran Sanz, Laura Furlong, Janet Piñero and Olga Valverde, and the investor partners: Frederic Abelló and the companies Prous Institute for Biomedical Research and Icrowd+D.

MedBioinformatics Solutions' offer will be based on DisGeNET, a tool developed by the Integrative Biomedical Informatics Group of IMIM and UPF's Research Programme on Biomedical Informatics (GRIB). Through the 600,000 associations between more than 17,000 genes and 24,000 human diseases it has amassed, it is currently "one of the resources to contain the most such information in the world", according to professor Ferran Sanz, a researcher and a founder of the company. Hence, the platform has aroused a great deal of interest in industry: "Companies have been writing to us for some time now to tell us that they would like to use the information in DisGeNET for their R&D", the scientist explains.

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Doctoral thesis of Kevin Pinto: "Development and Validation of Pharmacoinformatic Similarity-based Tools for the Safety Assessment of Chemicals"

N​ext ​friday 31st of January at ​9:00, ​Kevin Pinto​, member of the ​PharmacoInformatics ​group of GRIB, will read his thesis: ​"Development and Validation of Pharmacoinformatic Similarity-based Tools for the Safety Assessment of Chemicals​"​.​ The event will take place at the Marie Curie room on the ground floor of PRBB. You are all invited to come. 

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Dr. Jordi Mestres


Jordi Mestres nomenat membre del Consell Científic de ChemBioFrance

Jordi Mestres, coordinador del grup de recerca en farmacologia de sistemes del GRIB, va ser oficialment nomenat el passat dia 10 de gener membre del Consell Científic de ChemBioFrance, una infraestructura nacional de recerca francesa dedicada al descobriment de petites molècules biològicament actives que reuneix quatre recursos i xarxes diferents: la col.lecció nacional de molècules (Chimiothèque Nationale), una xarxa de plataformes de cribratge, una plataforma de quimioinformàtica i una xarxa de plataformes per a l'avaluació del metabolisme i seguretat de molècules. Segons Jordi Mestres, "ChemBioFrance representa una aposta estratègica per integrar i gestionar tots els elements essencials en el descobriment de nous fàrmacs des d'una infraestructura pública. És un autèntic privilegi formar part del seu Consell Científic i poder contribuïr al desenvolupament d'aquesta iniciativa pionera a Europa".

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Thesis defense of William Blevins: "Evolutionary dynamics of transcriptional and translational regulation in yeast"

Next friday 17th of January at 10:00AMWilliam Blevins, member of the Evolutionary Genomics group of GRIB, will read his thesis: "Evolutionary dynamics of transcriptional and translational regulation in yeast".

The event will take place at the Ramon y Cajal room on the ground floor of PRBB. You are all invited to come. 

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Doctoral thesis of Tomasz Maciej Stępniewski : "Unraveling the complex signaling behavior of neurotransmitters and their receptors in the brain"

Next thursday 9th of January at 14:00, Tomek Stepniewski, member of  the GPCR Drug Discovery group of GRIB, will read his thesis: "Unraveling the complex signaling behavior of neurotransmitters and their receptors in the brain".

The event will take place at the Marie Curie room on the ground floor of PRBB. You are all invited to come. 

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El GRIB participa en la reunión de la red de bioinformática traslacional TransBioNet

El objetivo principal de TransBioNet es crear un foro de expertos donde los bioinformáticos que trabajan en entornos de investigación sanitaria compartan las mejores prácticas y experiencias de trabajo, tengan acceso temprano a los últimos desarrollos tecnológicos y directrices de organizaciones e iniciativas. El trabajo de la red se centra en tres pilares principales: estándares y evaluaciones comparativas, modelos de sostenibilidad y actividades de formación. 

La Red de Bioinformática Traslacional, TransBioNet, considerada de excelencia por el Ministerio de Ciencia, Innovación y Universidades, e impulsada y coordinada por el Instituto Nacional de Bioinformática, es una plataforma tecnológica del Instituto de Salud Carlos III. La red está integrada por más de 35 unidades de apoyo bioinformático a lo largo del país. Dada su naturaleza altamente colaborativa, TransBioNet está abierta a cualquier unidad de bioinformática vinculada a entornos sanitarios o servicios de apoyo de bioinformática en instituciones de investigación biomédica.

Ver noticia completa en la web del INB

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The Project CompBioMed 2 started on 1st October 2019 and will run for another 4 years.

The Computational Science Group of GRIB led by Gianni de Fabritiis is involved on this project and will have a central role regarding research on biomedical science, both with simulation methods and deep learning based applications. The group will also be working towards integrating results from modelling and simulation data with clinical and/or experimental data, supporting the combination of high-throughput data analytics with HPC based results, which will provide users a way to leverage the results produced by CompBioMed's research.

Read more about the project at

Read more about other projects of the Computational Science Group of GRIB

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