Thesis defense of Sonja Haenzelmann: "Pathway-centric approaches to the analysis of high-throughput genomics data"

On thursday, 11th of October, Sonja Haenzelmann, member of the Functional Genomics Group of GRIB (IMIM-UPF) will defend her thesis at 11:30 at Xipre Room of PRBB.

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No podem entendre una malaltia ni el seu tractament des d'un sol àmbit científic

Entrevista a Ferran Sanz, Director del GRIB, sobre las jornades de debat Beyond Omics Revolutions: Integrative Knowledge Management for Empowered Healthcare and Research organitzades per B·Debate International Center for Scientific Debate Barcelona i que van reunir més d’una vintena dels científics capdavanters en bioinformàtica i informàtica mèdica dels centres de recerca de referència al món al juliol 2012 a Barcelona.

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Thesis defense of Emre Guney: "Role of network topology based methods in discovering novel gene-phenotype associations"


On Tuesday, 25th of September, Emre Guney, member of the Structural Bioinformatics Group of GRIB (IMIM-UPF) will defend his thesis at 11:00 in the Auditorium of PRBB.

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Beyond Omics Revolutions: Integrative Knowledge Management for Empowered Healthcare and Research

These debate sessions led by Ferran Sanz (GRIB Director) and coorganized by the GRIB (IMIM-UPF) and the Internatinal Center for Scientific Debate B·Debate will take place the 3rd, 4th and 5th of July and will bring together scientists and specialists from the many disciplines related to biomedical informatics in order to discuss the challenges, needs and opportunities of developing translational bioinformatics as a key tool for achieving more effective and personalized medicine.

Place: CaixaFòrum Barcelona and PRBB Auditorium

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Bio-, Medical- and Neuroinformatics supporting Neurosciences

El proper 6 de juliol el GRIB (IMIM-UPF) organitza una sessió de treball que porta per títol "Bio-, Medical- and Neuroinformatics supporting Neurosciences", que pretén reunir neurocientífics i clínics amb l'objectiu de discutir la integració dels mètodes computacionals i les tecnologies utilitzades en Neurociències, per tal d'organitzar, gestionar i accedir al coneixement neurocientífic. L'assistència al workshop és gratuïta però cal registrarse abans del dia 27 de juny. Per més informació contacteu amb Maria Saarela (

Place: Barcelona Biomedical Research Park (PRBB) 

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Thesis of Ignasi Buch: "Investigation of protein-ligand interactions using high-throughput all-atom molecular dynamics simulations"

On Friday, 29th of June, Ignasi Buch, member of the Computational Biophysics Group of GRIB (IMIM-UPF) will defend his thesis at 15:00 in the Auditorium of PRBB.

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GRIB participates at BIO Boston 2012, the top biotechnology convention in the world

Connect, partner and innovate. This is the slogan for the twentieth edition of the BIO International Convention, held 18 to 21 June 2012 in the city of Boston (Massachusetts, United States). BIO is the most important international business meeting in the biotechnology arena. This year, it will bring together more than 15,000 delegates from 65 countries, more than 900 exhibitors and 1,800 companies. In addition to the exhibition area, it also features a Business Forum for partnering meetings, which in 2011 generated more than 21,000 one-to-one meetings.

The GRIB (IMIM-UPF) takes part of the Catalan delegation made up of 50 companies and 22 organizations from the biotechnology and biomedicine sector. At the 2012 edition, Spain will have the most important international pavilion, with Catalonia making up more than 60%, ahead of countries like Brazil, China, India and Russia. The Spanish pavilion will be located at a strategic point, just in front of the host State of Massachusetts.

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Thesis of Khademul Islam: Delineating epigenetic regulatory mechanisms of cell proliferation and differentiation"

On Monday, 25th of June, Khademul Islam, member of the Biomedical Genomics Group of GRIB (IMIM-UPF) will defend his thesis at 14:00 in the Auditorium of PRBB.

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En la complexitat dels éssers vius intervenen propietats físico-químiques del medi cel·lular

Un treball dirigit per Eduardo Eyras, investigador ICREA i responsable del Grup de Regulació Genòmica del GRIB (IMIM-UPF) mostra com les formes o estructures secundàries d'ARN regulen l'splicing o empalmament alternatiu en cèl·lules de llevat (Saccharomyces cerevisiae) emprades com a model experimental.

S'ha comprovat que aquestes conformacions secundàries de l'ARN estan modificades per propietats físiques i químiques intrínseques de la cèl·lula, com ara la temperatura i el pH.

Treball de referència:  Plass M, Codony-Servat C, Ferreira PG, Vilardell J, Eyras E. RNA secondary structure mediates alternative 3'ss selection in Saccharomyces cerevisiae. RNA, 2012.

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eTOX makes progress on predictive toxicology

IMI project eTOX, coordinated by GRIB (IMIM-UPF) is making progress towards its goal of developing a predictive toxicology system called eTOXsys, which is now at the prototype stage. In a recent article in the International Journal of Molecular Sciences, the eTOX partners describe eTOXsys as 'a software tool able to provide useful toxicological risk and hazard assessment.' Users will simply need to enter a small amount of information, such as the structure of the compound they are interested in, and the system will use a series of advanced models to deliver information on the likelihood of potential toxicity of the compound.

Article reference: Briggs K, Cases M, Heard DJ, Pastor M, Pognan F, Sanz F, Schwab CH, Steger-Hartmann T, Sutter A, Watson DK, Wichard JD. Inroads to Predict in Vivo Toxicology -An Introduction to the eTOX Project. Int J Mol Sci, 2012; 13(3), 3820-3846. PMID 22489185. DOI 10.3390/ijms13033820.

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