Thesis lecture of Ismael Rodríguez Espigares: "GPCRmd - A web platform for collection, visualization and analysis of molecular dynamics data for G protein-coupled receptors"

Next Wednesday, 4th April 2018 at 10h, Ismael Rodríguez Espigares, member of the GPCR drug discovery group of GRIB will defense his thesis "GPCRmd - A web platform for collection, visualization and analysis of molecular dynamics data for G protein-coupled receptors" at the Charles Darwin room, placed at the inner square of the PRBB building (Dr. Aiguader, 88).You are all invited to this event.

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First genetic study of primate hibernation in their natural environment

The Evolutionary Genomics research group of  GRIB (IMIM-UPF), led by Mar Albà, has just published an article in the journal Molecular Ecology providing the results of a study that has identified which genes participate (change their expression) in the hibernation state of hairy-eared dwarf lemurs, which belong to the only group of primates that has the ability to hibernate. These small mammals store fats in their tails, allowing them to survive the months of shortage, and which they use as fuel during hibernation. Hibernation is a response to the lack of resources we normally associate with winter, but which can occur in other conditions of scarcity, such as in desert areas or, for example, during the dry season in Madagascar.

"These types of studies put unique species like this in the spotlight and serve to show that we must preserve our biodiversity. While we continue to dream about spacecraft and interstellar travel, we must not forget that everything starts with a small lemur buried deep in the Madagascan jungle", explains José Luis Villanueva-Cañas.

Reference article: Faherty SL*, Villanueva-Cañas JL*, Blanco MB, Albà MM, Yoder AD. Transcriptomics in the wild: hibernation physiology in free-ranging dwarf lemursMolecular Ecology, 29 Jan 2018

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XI Conferencia anual de las plataformas de investigación biomédica

Los días 5 y 6 de marzo se celebró en Barcelona la XI Conferencia Anual de las Plataformas Tecnológicas de Investigación Biomédica: Medicamentos Innovadores, Nanomedicina,  Tecnología Sanitaria y Mercados Biotecnológicos, en la que se presentaron diferentes avances en el ámbito de la innovación biomédica disruptiva en el abordaje de diferentes patologías.

La conferencia contó con la participación de más de 50 ponentes y 250 asistentes del sector público y privado. Ferran Sanz, Director del GRIB, junto con Javier Urzay, ambos co-Presidentes de la Plataforma Tecnológica Española de Medicamentos Innovadores, presentaron las actividades realizadas por esta plataforma en 2017

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ECTB 2018 speakers


Join the 3rd European Conference on Translational Bioinformatics: Biomedical Big Data Supporting Precision Medicine

The conference will be held at Barcelona Biomedical Research Park (PRBB) on April 16-17th 2018. This meeting follows on from the success of the European Conference on Translational Bioinformatics (ECTB) series hold in 2016 at the University of Copenhagen, Denmark; and in 2017 at the European Bioinformatics Institute, UK. As in past editions, the 2018 meeting will bring together scientists, developers, and entrepreneurs who are interested in translating genomics and bioinformatics research into healthcare tools and services. The meeting will be relevant for researchers, computational biologists and entrepreneurs from start-ups and established companies interested in epidemiology, cancer genomics and precision medicine.

The Conference is organized by the GRIB (IMIM-UPF) jointly with BSC and supported by the EU project MedBioinformatics and the Spanish Institute of Bioinformatics (INB).

Click here for Registration

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Thesis lecture of Mari Carmen Carrascosa: "Next generation of informatics tools for big data analytics in drug discovery"

Next Tuesday 20th of March at 11h, Mari Carmen Carrascosa , member of the Systems Pharmacology group of GRIB will defense her thesis "Next generation of informatics tools for big data analytics in drug discovery" at the Classroom number 61.127, placed at the first floor of the Doctor Aiguader building (Dr. Aiguader 80). You are all invited to this event.

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8 de març: Concentració pel dia de la dona treballadora

El dijous 8 de març hi ha convocada una concentració a les 11'30h a la plaça interior del PRBB amb motiu del dia de la dona treballadora. El Dia Internacional de les Dones o Dia de la Dona Treballadora és una commemoració anual reconeguda per l'Organització de les Nacions Unides i que denuncia el sexisme i la desigualtat de drets i oportunitats entre homes i dones.

Aquest mateix dia hi ha dues concentracions reivindicatives més, una convocada per les entitats sindicals a les 12 del migdia davant dels Ajuntaments i una a les 18,30 hores, a Passeig de Gràcia amb Diagonal, convocada per diverses organitzacions i institucions per a la celebració d' una manifestació unitària.

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El GRIB ha aconseguit un doctorat industrial en la convocatòria del 2017

El GRIB ha obtingut un ajut de Doctorat Industrial  a la convocatòria 2017 d'aquest programa gestionat per l'AGAUR que vol afavorir la transferència de coneixement al sector productiu.

El projecte anomenat "Play Molecule: Developing a web platform for biomedical applications" anirà a càrrec del doctorand Alejandro Varela, que tindrà com a director de tesi Gianni de Fabritiis, professor d'investigació ICREA i cap del grup de recerca en Biofísica Computacional del GRIB (IMIM-UPF).

El projecte, que es realitzarà amb l'empresa Acellera Labs, consistirà en el desenvolupament de noves eines bioinformàtiques estructurals i la seva implementació a, una plataforma en línia que ofereix solucions bioinformàtiques a problemes comuns en aquest camp.

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eTRANSAFE 2nd Consortium Meeting in Basel

The 2nd eTRANSAFE Consortium Meeting was held in Basel (Switzerland) on the 6th and 7th of February 2018, where members of the 26 partners of the Consortium met to share research outcomes from the first 6 months of the project life, as well as to discuss on project specific topics such as Data collection, interoperability and integration. In addition to presentations from the 10 Work Packages, parallel sessions were organised to emphasise efforts on Modelling and Data Sources.

eTRANSAFE is expected to build upon the success of eTOX, for this the use of eTOX assets such as eTOXsys and OntoBrowser was addressed during the meeting. The need to develop an adequate sustainability plan from the very beginning of the project, and the importance of promoting and disseminating the information and the knowledge generated were also discussed, as the creation of a task force aimed at addressing the collection of data (both preclinical and clinical) by the EFPIA companies from a common perspective.

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The 2nd annual conference Bermuda Principles - Impact on Splicing is coming

The 2nd annual conference Bermuda Principles - Impact on Splicing (BPIS) will be held on February 21 - 25th, 2018. Eduardo Eyras, head of the Computational RNA Biology group of GRIB (UPF-IMIM) takes part in the organization of this event.

The inaugural BPIS Conference that took place in February 2017 was a great success, consolidating it as annual event on the scientific calendar. In 2018 this exciting conference will feature a distinguished Keynote Lecture by Professor Adrian Krainer, presentations by six keynote speakers representing a wealth of countries including Italy, Scotland, England and the USA, and a further array of speakers from the USA, Switzerland, South Africa and Australia. The conference topics include: Splicing mechanisms; RNA structure; RNA - protein interactions; Bioinformatics; Splicing and disease; Links to transcription; Therapeutics and translational applications.

For further information about the conference please visit the website htps://

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Project eTOX close out meeting held in Brussels

On January 25th, the eTOX Executive Committee members François Pognan (Novartis Pharma), Ferran Sanz (FIMIM), Thomas Steger-Hartmann (BHC) and Carlos Díaz (SYNAPSE) held the close out meeting of the eTOX project at the IMI´s offices in Brussels. IMI´s Executive Director Dr Pierre Meulien also attended the meeting. The main points addressed during the meeting were project's objectives and outcomes, impact, sustainability and lessons learned.

The eTOX project stems from the very first IMI Call (it started in 2010) and was the very first IMI project coordinated by FIMIM. The project successfully ended in December 2016. With a budget of over 18.5 million €, the project was undertaken by a consortium of 30 organisations led by Novartis, among which 13 EFPIA companies, 11 academic partners, and 6 SMEs. The eTOX project aimed to build a toxicology database and novel software tools to better predict in-vivo toxicology of new chemical entities in early stages of the drug development pipeline.

The eTOX project leaves behind as main assets: eTOXsys - a tool to facilitate the safety assessment of new drug candidates; OntoBrowser - a tool to support community-based ontology development; eTOXlab - a platform for the development and maintenance of the models. These tools are an important legacy that will be further used within eTRANSAFE, an IMI-2 project recently started, that is expected to build upon the success of eTOX.

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