PhD Thesis - Computational Genomics > Biomedical Genomics - Computational Genomics

Jené, A. Integrative study of the regulatory and epigenomic programs involved in cancer development. University Pompeu Fabra. Director: López-Bigas, N. April, 2013.

2013

Original articles in indexed journals - Computational Genomics > Biomedical Genomics - Computational Genomics

de la Rica L, Urquiza JM, Gómez-Cabrero D, Islam AB, López-Bigas N, Tegnér J, Toes RE, Ballestar E. Identification of novel markers in rheumatoid arthritis through integrated analysis of DNA methylation and microRNA expression. J Autoimmun, 2013; 41 6-16 . PMID: 23306098 . DOI: 10.1016/j.jaut.2012.12.005.

2013

Original articles in indexed journals - Computational Genomics > Biomedical Genomics - Computational Genomics

Tamborero D, Lopez-Bigas N, Gonzalez-Perez A. Oncodrive-CIS: A Method to Reveal Likely Driver Genes Based on the Impact of Their Copy Number Changes on Expression. PLoS One, 2013; 8(2). PMID: 23408991 . DOI: 10.1371/journal.pone.0055489.

2013

Original articles in indexed journals - Computational Genomics > Biomedical Genomics - Computational Genomics

Hernando H, Shannon-Lowe C, Islam AB, Al-Shahrour F, Rodriguez-Ubreva J, Rodriguez-Cortez VC, Javierre BM, Mangas C, Fernandez AF, Parra M, Delecluse HJ, Esteller M, Lopez-Granados E, Fraga MF, Lopez-Bigas N, Ballestar E. The B cell transcription program mediates hypomethylation and overexpression of key genes in Epstein-Barr virus-associated proliferative conversion. Genome Biol, 2013; 15;14(1):R3. PMID: 23320978 .

2013

Other - Computational Genomics > Biomedical Genomics - Computational Genomics

Schroeder MP, Gonzalez-Perez A, Lopez-Bigas N. Visualizing multidimensional cancer genomics data. Genome Med, 2013; 31;5(1):9. PMID: 23363777 . DOI: 10.1186/gm413.

2013

Other - Computational Genomics > Biomedical Genomics - Computational Genomics

Gonzalez-Perez A, Deu-Pons J, Lopez-Bigas N. Improving the prediction of the functional impact of cancer mutations by baseline tolerance transformation. Genome Med, 2012;4(11):89. PMID: 23181723 .

2012

Original articles in indexed journals - Computational Genomics > Biomedical Genomics - Computational Genomics

Pippa R, Espinosa L, Gundem G, Garcia-Escudero R, Dominguez A, Orlando S, Gallastegui E, Saiz C, Besson A, Pujol MJ, Lopez-Bigas N, Paramio JM, Bigas A, Bachs O. p27(Kip1) represses transcription by direct interaction with p130/E2F4 at the promoters of target genes. Oncogene, 2012; 31 (38):4207-4220. PMID: 22179826 . DOI: 10.1038/onc.2011.582.

2012

Original articles in indexed journals - Computational Genomics > Biomedical Genomics - Computational Genomics

Gonzalez-Perez A, Lopez-Bigas N. Functional impact bias reveals cancer drivers. Nucleic Acids Res, 2012; 40; 21: e169. PMID: 22904074 . DOI: 10.1093/nar/gks743.

2012

Original articles in indexed journals - Computational Genomics > Biomedical Genomics - Computational Genomics

Bayarmagnai B, Nicolay BN, Islam AB, Lopez-Bigas N, Frolov MV. Drosophila GAGA factor is required for full activation of the dE2F1-Yki/Sd transcriptional program. Cell Cycle, 2012;11(22) : 4191-4202. PMID: 23070566 . DOI: 10.4161/cc.22486.

2012

Original articles in indexed journals - Computational Genomics > Biomedical Genomics - Computational Genomics

Beshiri ML, Holmes KB, Richter WF, Hess S, Islam AB, Yan Q, Plante L, Litovchick L, Gévry N, Lopez-Bigas N, Kaelin WG Jr, Benevolenskaya EV. Coordinated repression of cell cycle genes by KDM5A and E2F4 during differentiation. P Natl Acad Sci USA, 2012;  109 (45): 18499-18504. PMID: 23093672 . DOI: 10.1073/pnas.1216724109.

2012