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Results 211 - 220 of about 1295

Original articles in indexed journals - Structural Bioinformatics

Vives-Adrian L, Lujan C, Oliva B, van der Linden L, Selisko B, Coutard B, Canard B, van Kuppeveld FJ, Ferrer-Orta C, Verdaguer N.The crystal structure of a Cardiovirus RNA-dependent RNA polymerase reveals an unusual conformation of the polymerase active site. J Virol, 2014. PMID: 24600002 . DOI: 10.1128/JVI.03502-13.

2014

Original articles in indexed journals - Structural Bioinformatics

Guney E, Oliva B. Analysis of the robustness of network-based disease-gene prioritization methods reveals redundancy in the human interactome and functional diversity of disease-genes. PLoS One, 2014; 9(4): e94686 . PMID: 24733074 . DOI: 10.1371/journal.pone.0094686. eCollection 2014..

2014

Original articles in indexed journals - Integrative Biomedical Informatics

Bravo A, Cases M, Queralt-Rosinach N, Sanz F, Furlong LI. A Knowledge-Driven Approach to Extract Disease-Related Biomarkers from the Literature. BioMed Research International, 2014: 253128. PMID: 24839601 . DOI: 10.1155/2014/253128.

2014

Original articles in indexed journals - Integrative Biomedical Informatics - PharmacoInformatics

Marti-Solano M, Birney E, Bril A, Della Pasqua O, Kitano H, Mons B, Xenarios I, Sanz F. Integrative knowledge management to enhance pharmaceutical R&D. Nat Rev Drug Discov, 2014;13(4): 239-40. PMID: 24687050 . DOI: 10.1038/nrd4290.

2014

Original articles in indexed journals - Integrative Biomedical Informatics - PharmacoInformatics - GPCR Drug Discovery

Selent J, Marti-Solano M, Rodríguez J, Atanes P, Brea J, Castro M, Sanz F, Loza MI, Pastor M. Novel insights on the structural determinants of clozapine and olanzapine multi-target binding profiles. Eur J Med Chem, 2014; 77C: 91-95 . PMID: 24631727 . DOI: 10.1016/j.ejmech.2014.02.058 APR 2014.

2014

Original articles in indexed journals - Systems Pharmacology

Spitzmüller A, Mestres J. Identification of host interactions for phenotypic antimalarial hits. J Cheminformatics, 2014; 6(Suppl 1):O12 . PMID: 24765110 .

2014

Original articles in indexed journals - Structural Bioinformatics

Fornes O, Garcia-Garcia J, Bonet J, Oliva B. On the Use of Knowledge-Based Potentials for the Evaluation of Models of Protein-Protein, Protein-DNA, and Protein-RNA Interactions. Adv Protein Chem Str, 2014; 94: 77-120 . PMID: 24629186 . DOI: 10.1016/B978-0-12-800168-4.00004-4..

2014

Original articles in indexed journals - Computational Biophysics

Bisignano P, Doerr S, Harvey MJ, Favia AD, Cavalli A, de Fabritiis G. Kinetic characterization of fragment binding in AmpC beta-lactamase by high-throughput molecular simulations. J Chem Inf Model, 2014; 54 (2): 362-366. PMID: 24444037 . DOI: 10.1021/ci4006063 FEB 2014.

2014

Original articles in indexed journals - Integrative Biomedical Informatics

Espinet B, Ferrer A, Bellosillo B, Nonell L, Salar A, Fernández-Rodríguez C, Puigdecanet E, Gimeno J, Garcia-Garcia M, Vela MC, Luño E, Collado R, Navarro JT, de la Banda E, Abrisqueta P, Arenillas L, Serrano C, Lloreta J, Miñana B, Cerutti A, Florensa L, Orfao A, Sanz F, Solé F, Dominguez-Sola D, Serrano S. Distinction between asymptomatic monoclonal B-cell lymphocytosis with cyclin D1 overexpression and mantle cell lymphoma: from molecular profiling to flow cytometry. Clin Cancer Res, 2014; 20: 1007-1019. PMID: 24352646 . DOI: 10.1158/1078-0432.CCR-13-1077.

2014

Original articles in indexed journals - Computational Genomics - group

Ferreira PG, Jares P, Rico D, Gómez-López G, Martínez-Trillos A, Villamor N, Ecker S, González-Pérez A, Knowles DG, Monlong J, Johnson R, Quesada V, Gouin A, Djebali S, López-Guerra M, Colomer D, Royo C, Cazorla M, Pinyol M, Clot G, Aymerich M, Rozman M, Kulis M, Tamborero D, Papasaikas P, Blanc J, Gut M, Gut I, Puente XS, Pisano DG, Martin-Subero JI, López-Bigas N, López-Guillermo A, Valencia A, López-Otín C, Campo E, Guigo R. Transcriptome characterization by RNA sequencing identifies a major molecular and clinical subdivision in chronic lymphocytic leukemia. Genome Res, 2014; 24 (2): 212-226. PMID: 24265505 . DOI: 10.1101/gr.152132.112.

2014



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