Original articles in indexed journals - Computational RNA Biology

Cifdaloz M, Osterloh L, Graña O, Riveiro-Falkenbach E, Ximénez-Embún P, Muñoz J, Tejedo C, Calvo TG, Karras P, Olmeda D, Miñana B, Gómez-López G, Cañon E, Eyras E, Guo H, Kappes F, Ortiz-Romero PL, Rodríguez-Peralto JL, Megías D, Valcárcel J, Soengas MS. Systems analysis identifies melanoma-enriched pro-oncogenic networks controlled by the RNA binding protein CELF1. Nat Commun, 2017; 8(1): 2249.. PMID: 29269732 . DOI: 10.1038/s41467-017-02353-y.

2017

Original articles in indexed journals - Integrative Biomedical Informatics - Systems Pharmacology - PharmacoInformatics

Sanz F, Pognan F, Steger-Hartmann T, Díaz C, Cases M, Pastor M, Marc P, Wichard J, Briggs K, Watson D, Kleinöder T, Yang C, Amberg A, Beaumont M, Brookes A, Brunak S, Cronin MTD, Ecker GF, Escher S, Greene N, Guzmán A, Hersey A, Jacques P, Lammens L, Mestres J, Muster W, Northeved H, Pinches M, Saiz J, Sajot N, Valencia A, van der Lei J, Vermeulen NPE, Vock E, Wolber G, Zamora I. Legacy data sharing to improve drug safety assessment: the eTOX project. Nature Reviews Drug Discovery, 2017; 16(12): 811-812 . PMID: 29026211 . DOI: 10.1038/nrd.2017.177.

2017

Original articles in indexed journals - Integrative Biomedical Informatics

Perera G, Pedersen L, Ansel D, Alexander M, Arrighi HM, Avillach P, Foskett N, Gini R, Gordon MF, Gungabissoon U, Mayer MA, Novak G, Rijnbeek P, Trifirò G, van der Lei J, Visser PJ, Stewart R. Dementia prevalence and incidence in a federation of European Electronic Health Record databases: The European Medical Informatics Framework resource. Alzheimers Dement, 2017. S1552-5260 (17) 32523-2 . PMID: 28734783 . DOI: 10.1016/j.jalz.2017.06.2270.

2017

Original articles in indexed journals - Systems Pharmacology

Sultana J, Calabró M, Garcia-Serna R, Ferrajolo C, Crisafulli C, Mestres J, Trifirò' G. Biological substantiation of antipsychotic-associated pneumonia: Systematic literature review and computational analyses. PLoS ONE, 2017; 12(10): e0187034 . PMID: 29077727 .

2017

Original articles in indexed journals - Computational Biophysics

Plattner N, Doerr S, De Fabritiis G, Noé F. Complete protein-protein association kinetics in atomic detail revealed by molecular dynamics simulations and Markov modelling. Nat Chem, 2017; 9(10): 1005-1011 . PMID: 28937668 . DOI: 10.1038/nchem.2785.

2017

Original articles in indexed journals - Integrative Biomedical Informatics

Gutiérrez-Sacristán A, Hernández-Ferrer C, González JR, Furlong LI. Psygenet2r: a R/Bioconductor package for the analysis of psychiatric disease genes. Bioinformatics, 2017 . PMID: 28961763 . DOI: 10.1093/bioinformatics/btx506.

2017

Original articles in indexed journals - Integrative Biomedical Informatics

Leist M, Ghallab A, Graepel R, Marchan R, Hassan R, Bennekou SH, Limonciel A, Vinken M, Schildknecht S, Waldmann T, Danen E, van Ravenzwaay B, Kamp H, Gardner I, Godoy P, Bois FY, Braeuning A, Reif R, Oesch F, Drasdo D, Höhme S, Schwarz M, Hartung T, Braunbeck T, Beltman J, Vrieling H, Sanz F, Forsby A, Gadaleta D, Fisher C, Kelm J, Fluri D, Ecker G, Zdrazil B, Terron A, Jennings P, van der Burg B, Dooley S, Meijer AH, Willighagen E, Martens M, Evelo C, Mombelli E, Taboureau O, Mantovani A, Hardy B, Koch B, Escher S, van Thriel C, Cadenas C, Kroese D, van de Water B, Hengstler JG. Adverse outcome pathways: opportunities, limitations and open questions. Arch Toxicol, 2017; 91(11): 3477-3505 . PMID: 29051992 . DOI: 10.1007/s00204-017-2045-3.

2017

Original articles in indexed journals - Integrative Biomedical Informatics - PharmacoInformatics

Lopez O, Sanz F, Pastor M. An automated tool for obtaining QSAR-ready series of compounds using semantic web technologies. Bioinformatics, 2017; 34(1): 131-133 . PMID: 28968713 . DOI: 10.1093/bioinformatics/btx566.

2017

Original articles in indexed journals - GPCR Drug Discovery

Ramírez-Anguita JM, Rodríguez-Espigares I, Guixà-González R, Bruno A, Varela-Rial A, Selent J. Membrane cholesterol effect on the 5-HT2A receptor: Insights into the lipid-induced modulation of an antipsychotic drug target. Biotechnol Appl Bioc, 2017 . PMID: 28877377 . DOI: 10.1002/bab.1608.

2017

Original articles in indexed journals - GPCR Drug Discovery

Iglesias A, Cimadevila M, la Fuente RA, Martí-Solano M, Cadavid MI, Cadavid MI, Selent J, Loza MI, Brea J. Serotonin 2A receptor disulfide bridge integrity is crucial for ligand binding to different signalling states but not for its homodimerization. Eur J Pharmacol, 2017 . PMID: 28899696 . DOI: 10.1016/j.ejphar.2017.09.011.

2017