Original articles in indexed journals - GPCR Drug Discovery

Sánchez-Melgar A, Albasanz JL^*, Guixà-González R, Saleh N, Selent J, Martín M. The antioxidant resveratrol acts as a non-selective adenosine receptor agonist. Free Radical Biol Med, 2019; 135: 261-273.. PMID: 30898665 . DOI: 10.1016/j.freeradbiomed.2019.03.019.

2019

Original articles in indexed journals - Integrative Biomedical Informatics - Functional Genomics

Gea J, Pascual S, Castro-Acosta AA, Hernández-Carcereny C, Castelo R, Marquez-Martin E, Montón C, Palou A, Faner R, Furlong LI, Seijo L, Sanz F, Torà M, Vilaplana C, Casadevall C, López-Campos JL, Monsó E, Peces-Barba G, Cosio BG, Agustí A, Anexo. Miembros del grupo BIOMEPOC. The BIOMEPOC Project: Personalized Biomarkers and Clinical Profiles in Chronic Obstructive Pulmonary Disease. Arch Bronconeumol, 2019; 55(2): 93-99. PMID: 30343952 . DOI: 10.1016/j.arbres.2018.07.026.

2019

Original articles in indexed journals - Computational Science

Skalic M, Jiménez Luna J, Sabbadin D, De Fabritiis G. Shape-Based Generative Modeling for de-novo Drug Design. J Chem Inf Model, 2019; 59 (3): 1205-1214. PMID: 30762364 . DOI: 10.1021/acs.jcim.8b00706.

2019

Original articles in indexed journals - Computational RNA Biology

Ruiz-Reche A, Indi JA, de la Rubia I, Eyras E. ReorientExpress: reference-free orientation of nanopore cDNA reads with deep learning. bioRxiv, 2019. DOI: 10.1101/553321.

2019

Original articles in indexed journals - Computational RNA Biology

Bueno C, Velasco-Hernandez T, Gutiérrez-Agüera F, Zanetti SR, Baroni ML, Sánchez-Martínez D, Molina O, Closa A, Agraz-Doblás A, Marín P, Eyras E, Varela I, Menéndez P. CD133-directed CAR T-cells for MLL leukemia: on-target, off-tumor myeloablative toxicity. Leukemia, 2019; 33, 2090-2125. PMID: 30778134 . DOI: 10.1038/s41375-019-0418-8.

2019

Original articles in indexed journals - Integrative Biomedical Informatics - Systems Pharmacology

Brennecke at al (including Quintana J, Mestres J). EU-OPENSCREEN: A Novel Collaborative Approach to Facilitate Chemical Biology. SLAS Discov, 2019; 11: 247255521881627. PMID: 30616481 . DOI: 10.1177/ 2472555218816276.

2019

Original articles in indexed journals - PharmacoInformatics

Radchenko T, Fontaine F, Morettoni L, Zamora I. Software-aided workflow for predicting protease-specific cleavage sites using physicochemical properties of the natural and unnatural amino acids in peptide-based drug discovery. PLoS One, 2019; 14(1): e0199270. PMID: 30620739 . DOI: 10.1371/journal.pone. 0199270.

2019

Original articles in indexed journals - Structural Bioinformatics

Sharma P, Lioutas A, Fernandez-Fuentes N, Quilez J, Carbonell-Caballero J, Wright RHG, Di Vona Ch, Le Dily F, Schüller R, Eick D, Oliva B, Beato M. Arginine Citrullination at the C-Terminal Domain Controls RNA Polymerase II Transcription. Mol Cell, 2019; 73 (1): 84-96.e7. PMID: 30472187 . DOI: 10.1016/ j.molcel.2018.10.016.

2019

PhD Thesis - Functional Genomics

Puigdevall P. Identification of genetic modifiers of penetrance in human inherited disease. Universitat Pompeu Fabra. Jan 17th, 2019. Thesis Director: Castelo R

2019

Original articles in indexed journals - Integrative Biomedical Informatics

Ronzano F, Gutiérrez-Sacristán A, Furlong LI. Comorbidity4j: a tool for interactive analysis of disease comorbidities over large patient datasets. Bioinformatics, 2019; btz061. PMID: 30689768 . DOI: 10.1093/ bioinformatics/btz061.

2019