Original articles in indexed journals - Integrative Biomedical Informatics - PharmacoInformatics - GPCR Drug Discovery

Martí-Solano M, Sanz F, Pastor M, Selent J. A dynamic view of molecular switch behavior at serotonin receptors: implications for functional selectivity. PLoS One, 2014; 9(10): e109312 . PMID: 25313636 . DOI: 10.1371/journal.pone.0109312.

2014

Original articles in indexed journals - Integrative Biomedical Informatics

Grosdidier S, Ferrer A, Faner R, Piñero J, Roca J, Cosío B, Agustí A, Gea J, Sanz F, Furlong LI. Network medicine analysis of COPD multimorbidities. Respir Res, 2014; 15(1): 111. PMID: 25248857 . DOI: 10.1186/s12931-014-0111-4.

2014

Other - Integrative Biomedical Informatics

Carbonell P, Trosset JY. Overcoming drug resistance through in silico prediction. Drug Discov Today Thecnol, 2014; 11: 101-7. PMID: 24847659 .

2014

Original articles in indexed journals - Integrative Biomedical Informatics - Systems Pharmacology

Horvath D, Lisurek M, Rupp B, Kühne R, Specker E, von Kries J, Rognan D, Andersson CD, Almqvist F, Elofsson M, Enqvist PA, Gustavsson AL, Remez N, Mestres J, Marcou G, Varnek A, Hibert M, Quintana J, Frank R. Design of a General-Purpose European Compound Screening Library for EU-OPENSCREEN. ChemMedChem, 2014; 9 (10):2309-2326. PMID: 25044981 . DOI: 10.1002/cmdc.201402126.

2014

Original articles in indexed journals - Integrative Biomedical Informatics - PharmacoInformatics

Carrió P, Pinto M, Ecker G, Sanz F, Pastor M. Applicability Domain Analysis (ADAN): A Robust Method for Assessing the Reliability of Drug Property Predictions. J Chem Inf Model, 2014; 54 (5): 1500-1511. PMID: 24821140 . DOI: 10.1021/ci500172z.

2014

Original articles in indexed journals - Integrative Biomedical Informatics - PharmacoInformatics - GPCR Drug Discovery

Selent J, Marti-Solano M, Rodríguez J, Atanes P, Brea J, Castro M, Sanz F, Loza MI, Pastor M. Novel insights on the structural determinants of clozapine and olanzapine multi-target binding profiles. Eur J Med Chem, 2014; 77C: 91-95 . PMID: 24631727 . DOI: 10.1016/j.ejmech.2014.02.058 APR 2014.

2014

Original articles in indexed journals - Integrative Biomedical Informatics - PharmacoInformatics

Marti-Solano M, Birney E, Bril A, Della Pasqua O, Kitano H, Mons B, Xenarios I, Sanz F. Integrative knowledge management to enhance pharmaceutical R&D. Nat Rev Drug Discov, 2014;13(4): 239-40. PMID: 24687050 . DOI: 10.1038/nrd4290.

2014

Original articles in indexed journals - Integrative Biomedical Informatics

Bravo A, Cases M, Queralt-Rosinach N, Sanz F, Furlong LI. A Knowledge-Driven Approach to Extract Disease-Related Biomarkers from the Literature. BioMed Research International, 2014: 253128. PMID: 24839601 . DOI: 10.1155/2014/253128.

2014

Original articles in indexed journals - Integrative Biomedical Informatics

Espinet B, Ferrer A, Bellosillo B, Nonell L, Salar A, Fernández-Rodríguez C, Puigdecanet E, Gimeno J, Garcia-Garcia M, Vela MC, Luño E, Collado R, Navarro JT, de la Banda E, Abrisqueta P, Arenillas L, Serrano C, Lloreta J, Miñana B, Cerutti A, Florensa L, Orfao A, Sanz F, Solé F, Dominguez-Sola D, Serrano S. Distinction between asymptomatic monoclonal B-cell lymphocytosis with cyclin D1 overexpression and mantle cell lymphoma: from molecular profiling to flow cytometry. Clin Cancer Res, 2014; 20: 1007-1019. PMID: 24352646 . DOI: 10.1158/1078-0432.CCR-13-1077.

2014

Original articles in indexed journals - Integrative Biomedical Informatics - Systems Pharmacology

Lopes P, Nunes T, Campos D, Furlong LI, Bauer-Mehren A, Sanz F, Carrascosa MC, Mestres J, Kors J, Singh B, van Mulligen E, Van der Lei J, Diallo G, Avillach P, Ahlberg E, Boyer S, Diaz C, Oliveira JL. Gathering and Exploring Scientific Knowledge in Pharmacovigilance. PLoS One, 2013; 11;8(12):e83016. PMID: 24349421 . DOI: 10.1371/journal.pone.0083016.

2013