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PhD Thesis

Pérez Llamas C. Computational approaches for integrative cancer genomics. University Pompeu Fabra. Thesis Director: Lopez-Bigas, N. December 18, 2015. 

2015

Original articles in indexed journals - Systems Pharmacology

Rubio-Perez C, Tamborero D, Schroeder MP, Antolin AA, Deu-Pons J, Perez-Llamas C, Mestres J, Gonzalez-Perez A, Lopez-Bigas N. In silico prescription of anticancer drugs to cohorts of 28 tumor types reveals novel targeting opportunities. Cancer Res, 2015; 75 (22): 1 DOI: 10.1158/1538-7445.TRANSCAGEN-A1-45.

2015

Original articles in indexed journals

Gama-Norton L, Ferrando E, Ruiz-Herguido C, Liu Z, Guiu J, Islam AB, Lee SU, Yan M, Guidos CJ, López-Bigas N, Maeda T, Espinosa L, Kopan R, Bigas A. Notch signal strength controls cell fate in the haemogenic endothelium. Nat Commun, 2015; 6: 8510 . PMID: 26465397 . DOI: 10.1038/ncomms9510.

2015

Original articles in indexed journals

Puente XS, Beà S, Valdés-Mas R, Villamor N, Gutiérrez-Abril J, Martín-Subero JI, Munar M, Rubio-Pérez C, Jares P, Aymerich M, Baumann T, Beekman R, Belver L, Carrio A, Castellano G, Clot G, Colado E, Colomer D, Costa D, Delgado J, Enjuanes A, Estivill X, Ferrando AA, Gelpí JL, González B, González S, González M, Gut M, Hernández-Rivas JM, López-Guerra M, Martín-García D, Navarro A, Nicolás P, Orozco M, Payer ÁR, Pinyol M, Pisano DG, Puente DA, Queirós AC, Quesada V, Romeo-Casabona CM, Royo C, Royo R, Rozman M, Russiñol N, Salaverría I, Stamatopoulos K, Stunnenberg HG, Tamborero D, Terol MJ, Valencia A, López-Bigas N, Torrents D, Gut I, López-Guillermo A, López-Otín C, Campo E. Non-coding recurrent mutations in chronic lymphocytic leukaemia. Nature, 2015; 526 (7574): 519-U115 . PMID: 26200345 . DOI: 10.1038/nature14666 OCT 22 2015.

2015

Original articles in indexed journals

Váraljai R, Islam AB, Beshiri ML, Rehman J, Lopez-Bigas N, Benevolenskaya EV. Increased mitochondrial function downstream from KDM5A histone demethylase rescues differentiation in pRB-deficient cells. Genes Dev, 2015; 1; 29 (17): 1817-34 . PMID: 26314709 . DOI: 10.1101/gad.264036.115 SEP 1 2015.

2015

Original articles in indexed journals

Creixell P, Reimand J, Haider S, Wu GM, Shibata T, Vazquez M, Mustonen V, Gonzalez-Perez A, Pearson J, Sander C, Raphael BJ, Marks DS, Ouellette BFF, Valencia A, Bader GD, Boutros PC, Stuart JM, Linding R, Lopez-Bigas N & Stein LD for the Mutation Consequences and Pathway Analysis working group of the International Cancer Genome Consortium. Pathway and network analysis of cancer genomes. Nat Methods, 2015; 12(7):615-621 . PMID: 26125594 . DOI: 10.1038/NMETH.3440.

2015

Original articles in indexed journals

Gallardo F, Padrón A, Garcia R, Rius C, González-Pérez A, Arumí M, Iglesias M, Nonell L, Bellosillo B, Segura S, Pujol RM, López-Bigas N, Bertran J, Bigas A, Espinosa L. Cytoplasmic accumulation of NCoR in malignant melanoma: consequences of altered gene repression and prognostic significance. Oncotarget, 2015; 6 (11): 9284-9294 . PMID: 25823659 .

2015

Original articles in indexed journals - Systems Pharmacology

Rubio-Perez C, Tamborero D, Schroeder MP, Antolin A, Deu-Pons J, Perez-Llamas C, Mestres J, Gonzalez-Perez A, Lopez-Bigas N. In Silico Prescription of Anticancer Drugs to Cohorts of 28 Tumor Types Reveals Targeting Opportunities. Cancer Cell, 2015; 27; 3: 319-321 . PMID: 25759023 . DOI: 10.1016/j.ccell.2015.02.007.

2015

Original articles in indexed journals

Barneda-Zahonero B, Collazo O, Azagra A, Fernández-Duran I, Serra-Musach J, Islam AB, Vega-García N, Malatesta R, Camós M, Gómez A, Román-González L, Vidal A, López-Bigas N, Villanueva A, Esteller M, Parra M. The transcriptional repressor HDAC7 promotes apoptosis and c-Myc downregulation in particular types of leukemia and lymphoma. Cell Death Dis, 2015; 6 . PMID: 25675295 . DOI: 10.1038/cddis.2014.594 FEB 2015.

2015

Original articles in indexed journals

Di Vona C, Bezdan D, Islam AB, Salichs E, López-Bigas N, Ossowski S, de la Luna S. Chromatin-wide Profiling of DYRK1A Reveals a Role as a Gene-Specific RNA Polymerase II CTD Kinase. Mol Cell, 2015; 57; 3: 506-520 . PMID: 25620562 . DOI: 10.1016/j.molcel.2014.12.026.

2015



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