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Results 21 - 30 of about 120

Original articles in indexed journals

Gama-Norton L, Ferrando E, Ruiz-Herguido C, Liu Z, Guiu J, Islam AB, Lee SU, Yan M, Guidos CJ, López-Bigas N, Maeda T, Espinosa L, Kopan R, Bigas A. Notch signal strength controls cell fate in the haemogenic endothelium. Nat Commun, 2015; 6: 8510 . PMID: 26465397 . DOI: 10.1038/ncomms9510.

2015

Original articles in indexed journals

Váraljai R, Islam AB, Beshiri ML, Rehman J, Lopez-Bigas N, Benevolenskaya EV. Increased mitochondrial function downstream from KDM5A histone demethylase rescues differentiation in pRB-deficient cells. Genes Dev, 2015; 1; 29 (17): 1817-34 . PMID: 26314709 . DOI: 10.1101/gad.264036.115 SEP 1 2015.

2015

Original articles in indexed journals

Creixell P, Reimand J, Haider S, Wu GM, Shibata T, Vazquez M, Mustonen V, Gonzalez-Perez A, Pearson J, Sander C, Raphael BJ, Marks DS, Ouellette BFF, Valencia A, Bader GD, Boutros PC, Stuart JM, Linding R, Lopez-Bigas N & Stein LD for the Mutation Consequences and Pathway Analysis working group of the International Cancer Genome Consortium. Pathway and network analysis of cancer genomes. Nat Methods, 2015; 12(7):615-621 . PMID: 26125594 . DOI: 10.1038/NMETH.3440.

2015

Original articles in indexed journals - Systems Pharmacology

Rubio-Perez C, Tamborero D, Schroeder MP, Antolin A, Deu-Pons J, Perez-Llamas C, Mestres J, Gonzalez-Perez A, Lopez-Bigas N. In Silico Prescription of Anticancer Drugs to Cohorts of 28 Tumor Types Reveals Targeting Opportunities. Cancer Cell, 2015; 27; 3: 319-321 . PMID: 25759023 . DOI: 10.1016/j.ccell.2015.02.007.

2015

Original articles in indexed journals

Gallardo F, Padrón A, Garcia R, Rius C, González-Pérez A, Arumí M, Iglesias M, Nonell L, Bellosillo B, Segura S, Pujol RM, López-Bigas N, Bertran J, Bigas A, Espinosa L. Cytoplasmic accumulation of NCoR in malignant melanoma: consequences of altered gene repression and prognostic significance. Oncotarget, 2015; 6 (11): 9284-9294 . PMID: 25823659 .

2015

Original articles in indexed journals

Di Vona C, Bezdan D, Islam AB, Salichs E, López-Bigas N, Ossowski S, de la Luna S. Chromatin-wide Profiling of DYRK1A Reveals a Role as a Gene-Specific RNA Polymerase II CTD Kinase. Mol Cell, 2015; 57; 3: 506-520 . PMID: 25620562 . DOI: 10.1016/j.molcel.2014.12.026.

2015

Original articles in indexed journals

Barneda-Zahonero B, Collazo O, Azagra A, Fernández-Duran I, Serra-Musach J, Islam AB, Vega-García N, Malatesta R, Camós M, Gómez A, Román-González L, Vidal A, López-Bigas N, Villanueva A, Esteller M, Parra M. The transcriptional repressor HDAC7 promotes apoptosis and c-Myc downregulation in particular types of leukemia and lymphoma. Cell Death Dis, 2015; 6 . PMID: 25675295 . DOI: 10.1038/cddis.2014.594 FEB 2015.

2015

Original articles in indexed journals

Biton A, Bernard-Pierrot I, Lou Y, Krucker C, Chapeaublanc E, Rubio-Pérez C, López-Bigas N, Kamoun A, Neuzillet Y, Gestraud P, Grieco L, Rebouissou S, de Reyniès A, Benhamou S, Lebret T, Southgate J, Barillot E, Allory Y, Zinovyev A, Radvanyi F. Independent component analysis uncovers the landscape of the bladder tumor transcriptome and reveals insights into luminal and Basal subtypes. Cell Rep, 2014;9(4):1235-45. PMID: 25456126 . DOI: 10.1016/j.celrep.2014.10.035.

2014

Original articles in indexed journals

Leiserson MD, Vandin F, Wu HT, Dobson JR, Eldridge JV, Thomas JL, Papoutsaki A, Kim Y, Niu B, McLellan M, Lawrence MS, Gonzalez-Perez A, Tamborero D, Cheng Y, Ryslik GA, Lopez-Bigas N, Getz G, Ding L, Raphael BJ. Pan-cancer network analysis identifies combinations of rare somatic mutations across pathways and protein complexes. Nat Genet, 2014; 47 (2): 106-114. PMID: 25501392 . DOI: 10.1038/ng.3168.

2014

Original articles in indexed journals

Guiu J, Bergen D, De Pater E, Islam A, Ayllón V, Gama-Norton L, Ruiz-Herguido C, González J, López-Bigas N, Menéndez P, Dzierzak E, Espinosa L, Bigas A*. Identification of Cdca7 as a novel Notch transcriptional target involved in hematopoietic stem cell emergence. J Exp Med, 2014; 211 (12): 2411-2423. PMID: 25385755 . DOI: 10.1084/jem.20131857.

2014



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