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Original articles in indexed journals

Gallardo F, Padrón A, Garcia R, Rius C, González-Pérez A, Arumí M, Iglesias M, Nonell L, Bellosillo B, Segura S, Pujol RM, López-Bigas N, Bertran J, Bigas A, Espinosa L. Cytoplasmic accumulation of NCoR in malignant melanoma: consequences of altered gene repression and prognostic significance. Oncotarget, 2015; 6 (11): 9284-9294 . PMID: 25823659 .

2015

Original articles in indexed journals - Systems Pharmacology

Rubio-Perez C, Tamborero D, Schroeder MP, Antolin A, Deu-Pons J, Perez-Llamas C, Mestres J, Gonzalez-Perez A, Lopez-Bigas N. In Silico Prescription of Anticancer Drugs to Cohorts of 28 Tumor Types Reveals Targeting Opportunities. Cancer Cell, 2015; 27; 3: 319-321 . PMID: 25759023 . DOI: 10.1016/j.ccell.2015.02.007.

2015

Original articles in indexed journals

Barneda-Zahonero B, Collazo O, Azagra A, Fernández-Duran I, Serra-Musach J, Islam AB, Vega-García N, Malatesta R, Camós M, Gómez A, Román-González L, Vidal A, López-Bigas N, Villanueva A, Esteller M, Parra M. The transcriptional repressor HDAC7 promotes apoptosis and c-Myc downregulation in particular types of leukemia and lymphoma. Cell Death Dis, 2015; 6 . PMID: 25675295 . DOI: 10.1038/cddis.2014.594 FEB 2015.

2015

Original articles in indexed journals

Di Vona C, Bezdan D, Islam AB, Salichs E, López-Bigas N, Ossowski S, de la Luna S. Chromatin-wide Profiling of DYRK1A Reveals a Role as a Gene-Specific RNA Polymerase II CTD Kinase. Mol Cell, 2015; 57; 3: 506-520 . PMID: 25620562 . DOI: 10.1016/j.molcel.2014.12.026.

2015

Original articles in indexed journals

Leiserson MD, Vandin F, Wu HT, Dobson JR, Eldridge JV, Thomas JL, Papoutsaki A, Kim Y, Niu B, McLellan M, Lawrence MS, Gonzalez-Perez A, Tamborero D, Cheng Y, Ryslik GA, Lopez-Bigas N, Getz G, Ding L, Raphael BJ. Pan-cancer network analysis identifies combinations of rare somatic mutations across pathways and protein complexes. Nat Genet, 2014; 47 (2): 106-114. PMID: 25501392 . DOI: 10.1038/ng.3168.

2014

Original articles in indexed journals

Biton A, Bernard-Pierrot I, Lou Y, Krucker C, Chapeaublanc E, Rubio-Pérez C, López-Bigas N, Kamoun A, Neuzillet Y, Gestraud P, Grieco L, Rebouissou S, de Reyniès A, Benhamou S, Lebret T, Southgate J, Barillot E, Allory Y, Zinovyev A, Radvanyi F. Independent component analysis uncovers the landscape of the bladder tumor transcriptome and reveals insights into luminal and Basal subtypes. Cell Rep, 2014;9(4):1235-45. PMID: 25456126 . DOI: 10.1016/j.celrep.2014.10.035.

2014

PhD Thesis

Schroeder, Michael Philipp. Analysis and visualization of multidimensional cancer genomics data. Universitat Pompeu Fabra. November, 21st 2014. Thesis Directors: López Bigas, Núria; González-Pérez, Abel

2014

Original articles in indexed journals

Guiu J, Bergen D, De Pater E, Islam A, Ayllón V, Gama-Norton L, Ruiz-Herguido C, González J, López-Bigas N, Menéndez P, Dzierzak E, Espinosa L, Bigas A*. Identification of Cdca7 as a novel Notch transcriptional target involved in hematopoietic stem cell emergence. J Exp Med, 2014; 211 (12): 2411-2423. PMID: 25385755 . DOI: 10.1084/jem.20131857.

2014

Original articles in indexed journals

Vento-Tormo R, Rodríguez-Ubreva J, Di Lisio L, Islam AB, Urquiza JM, Hernando H, López-Bigas N, Shannon-Lowe C, Martínez N, Montes-Moreno S, Piris MA, Ballestar E. NF-KappaB directly mediates epigenetic deregulation of common microRNAs in Epstein-Barr virus-mediated transformation of B-cells and in lymphomas. Nucleic Acids Res, 2014; 42 (17): 11025-11039. PMID: 25200074 . DOI: 10.1093/nar/gku826 SEP 29 2014.

2014

Original articles in indexed journals

Gobbi A, Iorio F, Dawson KJ, Wedge DC, Tamborero D, Alexandrov LB, Lopez-Bigas N, Garnett MJ, Jurman G, Saez-Rodriguez J. Fast randomization of large genomic datasets while preserving alteration counts. Bioinformatics, 2014; 30(17):i617-i623. PMID: 25161255 . DOI: 10.1093/bioinformatics/btu474.

2014



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