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Results 11 - 20 of about 77

Original articles in indexed journals - GPCR Drug Discovery

Koklič T, Hrovat A, Guixà-González R, Rodríguez-Espigares I, Navio D, Frangež R, Uršič M, Kubale V, Plemenitaš A, Selent J, Šentjurc M, Vrecl M. Electron Paramagnetic Resonance Gives Evidence for the Presence of Type 1 Gonadotropin-Releasing Hormone Receptor (GnRH-R) in Subdomains of Lipid Rafts. Molecules. 2021; 26(4):973. PMID: 33673080 . DOI: 10.3390/molecules26040973.

2021

Original articles in indexed journals - GPCR Drug Discovery

Ågren R, Zeberg H, Stępniewski TM, Free RB, Reilly SW, Luedtke RR, Århem P, Ciruela F, Sibley DR, Mach RH, Selent J, Nilsson J, Sahlholm K. Ligand with Two Modes of Interaction with the Dopamine D2 Receptor-An Induced-Fit Mechanism of Insurmountable Antagonism. ACS Chem Neurosci, 2020; 11(19):3130-3143. PMID: 32865974 . DOI: 10.1021/acschemneuro.0c00477.

2020

Original articles in indexed journals - GPCR Drug Discovery

Dwivedi-Agnihotri H, Chaturvedi M, Baidya M, Stepniewski TM, Pandey S, Maharana J, Srivastava A, Caengprasath N, Hanyaloglu AC, Selent J, Shukla AK. Distinct phosphorylation sites in a prototypical GPCR differently orchestrate beta-arrestin interaction, trafficking, and signaling. Sci Adv, 2020; 6 (37): eabb8368. PMID: 32917711 . DOI: 10.1126/sciadv.abb8368.

2020

Original articles in indexed journals - GPCR Drug Discovery

Baidya M, Kumari P, Dwivedi-Agnihotri H, Pandey S, Chaturvedi M, Stepniewski T, Kawakami K, Cao Y, Laporte SA, Selent J, Inoue A, Shukla AK. Key phosphorylation sites in GPCRs orchestrate the contribution of ?-Arrestin 1 in ERK1/2 activation. Embo Rep, 2020; e49886. PMID: 32715625 . DOI: 10.15252/embr.201949886.

2020

Original articles in indexed journals - GPCR Drug Discovery

Torrens-Fontanals M, Stepniewski TM, Aranda-García D, Morales-Pastor A, Medel-Lacruz B, Selent J. How Do Molecular Dynamics Data Complement Static Structural Data of GPCRs. Int J Mol Sci, 2020; 21(16):5933. PMID: 32824756 . DOI: 10.3390/ijms21165933.

2020

Original articles in indexed journals - Integrative Biomedical Informatics - Computational Science - GPCR Drug Discovery

Rodríguez-Espigares I, Torrens-Fontanals M, Tiemann JKS et al (including Selent J, Sanz F, de Fabritiis G). GPCRmd uncovers the dynamics of the 3D-GPCRome. Nat Methods, 2020; 17(8): 777-787. PMID: 32661425 . DOI: 10.1038/s41592-020-0884-y  .

2020

Original articles in indexed journals - GPCR Drug Discovery

Jaiteh M, Rodríguez-Espigares I, Selent J, Carlsson J. Performance of virtual screening against GPCR homology models: Impact of template selection and treatment of binding site plasticity. PLoS Comput Biol, 2020; 16(3): e1007680. PMID: 32168319 . DOI: 10.1371/journal.pcbi.1007680.

2020

Original articles in indexed journals - GPCR Drug Discovery

Sommer ME, Selent J, Carlsson J, De Graaf C, Gloriam DE, Keseru GM, Kosloff M, Mordalski S, Rizk A, Rosenkilde MM, Sotelo E, Tiemann JKS, Tobin A, Vardjan N, Waldhoer M, Kolb P. The European Research Network on Signal Transduction (ERNEST): Toward a Multidimensional Holistic Understanding of G Protein-Coupled Receptor Signaling. ACS Pharmacol Transl Sci, 2020; 3(2): 361-370. PMID: 32296774 . DOI: 10.1021/acsptsci.0c00024.

2020

PhD Thesis - GPCR Drug Discovery

Stępniewski T.  Unraveling the complex signaling behavior of neurotransmitters and their receptors in the brain. Universitat Pompeu Fabra. January, 9th 2020. Thesis Director: Selent J.

2020

Other - GPCR Drug Discovery

Garcia Silva A, Marti Solano M, Selent J, Loza Garcia M, Castro Perez M. Quantification of functional bias of serotonin 5-HT2A receptor agonists and validation of structural hypotheses on functional selectivity at 5-HT2A receptor. BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY 125, 44-44 2019

2019



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