Original articles in indexed journals - Integrative Biomedical Informatics

Furlong LI. Human diseases through the lens of network biology.  Trends Genet, 2012; 29 (3):150-159. PMID: 23219555 . DOI: 10.1016/j.tig.2012.11.004.

2012

Original articles in indexed journals - Computational Genomics - group

Gonzalez-Perez A, Lopez-Bigas N. Functional impact bias reveals cancer drivers. Nucleic Acids Res, 2012; 40; 21: e169. PMID: 22904074 . DOI: 10.1093/nar/gks743.

2012

Original articles in indexed journals - Systems Pharmacology

Oprea TI, Mestres J. Drug Repurposing: Far Beyond New Targets for Old Drugs. AAPS Journal, 2012; 14(4): 759-763 . PMID: 22826034 . DOI: 10.1208/s12248-012-9390-1.

2012

Original articles in indexed journals - Computational Genomics - group

Bayarmagnai B, Nicolay BN, Islam AB, Lopez-Bigas N, Frolov MV. Drosophila GAGA factor is required for full activation of the dE2F1-Yki/Sd transcriptional program. Cell Cycle, 2012;11(22) : 4191-4202. PMID: 23070566 . DOI: 10.4161/cc.22486.

2012

Original articles in indexed journals - Computational Genomics - group

Beshiri ML, Holmes KB, Richter WF, Hess S, Islam AB, Yan Q, Plante L, Litovchick L, Gévry N, Lopez-Bigas N, Kaelin WG Jr, Benevolenskaya EV. Coordinated repression of cell cycle genes by KDM5A and E2F4 during differentiation. P Natl Acad Sci USA, 2012;  109 (45): 18499-18504. PMID: 23093672 . DOI: 10.1073/pnas.1216724109.

2012

Original articles in indexed journals - Systems Pharmacology

Montolio M, Gregori-Puigjane E, Pineda D, Mestres J, Navarro P. Identification of small molecule inhibitors of Amyloid ?-induced neuronal apoptosis acting through the imidazoline I2 receptor. J Med Chem, 2012; 55 (22): 9838-9846. PMID: 23098038 . DOI: 10.1021/jm301055g.

2012

Original articles in indexed journals - Computational Genomics - group

Pippa R, Espinosa L, Gundem G, Garcia-Escudero R, Dominguez A, Orlando S, Gallastegui E, Saiz C, Besson A, Pujol MJ, Lopez-Bigas N, Paramio JM, Bigas A, Bachs O. p27(Kip1) represses transcription by direct interaction with p130/E2F4 at the promoters of target genes. Oncogene, 2012; 31 (38):4207-4220. PMID: 22179826 . DOI: 10.1038/onc.2011.582.

2012

Original articles in indexed journals - Computational RNA Biology - Computational Genomics - group

Nadal-Ribelles M, Conde N, Flores O, Gonzalez-Vallinas J, Eyras E, Orozco M, de Nadal E, Posas F. Hog1 bypasses stress-mediated down-regulation of transcription by RNA polymerase II redistribution and chromatin remodeling. Genome Biol, 2012; 13(11): R106. PMID: 23158682 . DOI: 10.1186/gb-2012-13-11-r106 2012.

2012

Original articles in indexed journals - Computational Genomics - group - Functional Genomics

Mahdi T, Hanzelmann S, Salehi A et al. Secreted frizzled-related protein 4 reduces insulin secretion and is overexpressed in type 2 diabetes. Cell metabolism, 2012; 16; 5: 625-33. PMID: 23140642 . DOI: 10.1016/j.cmet.2012.10.009.

2012

Original articles in indexed journals - Computational Science

Harvey MJ, De Fabritiis G. High-throughput molecular dynamics: The powerful new tool for drug discovery. Drug Discovery Today, 2012; 17(19-20):1059-62. PMID: 22504137 . DOI: 10.1016/j.drudis.2012.03.017.

2012