Original articles in indexed journals - Integrative Biomedical Informatics

Nevado-Holgado AJ, Ribe E, Thei L, Furlong LI, Mayer MA, Quan J, Richardson JC, Cavanagh J, Consortium N, Lovestone S. Genetic and Real-World Clinical Data, Combined with Empirical Validation, Nominate Jak-Stat Signaling as a Target for Alzheimer's Disease Therapeutic Development. Cells, 2019; 8(5): E425. PMID: 31072055 . DOI: 10.3390/cells8050425.

2019

Original articles in indexed journals - Integrative Biomedical Informatics - Structural Bioinformatics

Aguirre-Plans J, Piñero J, Sanz F, Furlong LI, Fernandez-Fuentes N, Oliva B, Guney E. GUILDify v2.0: A tool to identify molecular networks underlying human diseases, their comorbidities and their druggable targets. J Mol Biol, 2019. pii: S0022-2836 (19) 30117-2.. PMID: 30851278 . DOI: 10.1016/ j.jmb.2019.02.027.

2019

Original articles in indexed journals - Integrative Biomedical Informatics - Functional Genomics

Gea J, Pascual S, Castro-Acosta AA, Hernández-Carcereny C, Castelo R, Marquez-Martin E, Montón C, Palou A, Faner R, Furlong LI, Seijo L, Sanz F, Torà M, Vilaplana C, Casadevall C, López-Campos JL, Monsó E, Peces-Barba G, Cosio BG, Agustí A, Anexo. Miembros del grupo BIOMEPOC. The BIOMEPOC Project: Personalized Biomarkers and Clinical Profiles in Chronic Obstructive Pulmonary Disease. Arch Bronconeumol, 2019; 55(2): 93-99. PMID: 30343952 . DOI: 10.1016/j.arbres.2018.07.026.

2019

Original articles in indexed journals - Integrative Biomedical Informatics - Systems Pharmacology

Brennecke at al (including Quintana J, Mestres J). EU-OPENSCREEN: A Novel Collaborative Approach to Facilitate Chemical Biology. SLAS Discov, 2019; 11: 247255521881627. PMID: 30616481 . DOI: 10.1177/ 2472555218816276.

2019

Original articles in indexed journals - Integrative Biomedical Informatics

Ronzano F, Gutiérrez-Sacristán A, Furlong LI. Comorbidity4j: a tool for interactive analysis of disease comorbidities over large patient datasets. Bioinformatics, 2019; 35 (18): 3530-3532. PMID: 30689768 . DOI: 10.1093/ bioinformatics/btz061.

2019

Original articles in indexed journals - Integrative Biomedical Informatics

Speck-Planche A. Combining Ensemble Learning with a Fragment-Based Topological Approach To Generate New Molecular Diversity in Drug Discovery: In Silico Design of Hsp90 Inhibitors. ACS Omega, 2018; 3(11): 14704- 14716. PMID: 30555986 . DOI: 10.1021/acsomega.8b02419.

2018

Original articles in indexed journals - Integrative Biomedical Informatics

Souza T, Trairatphisan P, Piñero J, Furlong LI, Saez-Rodriguez J, Kleinjans J, Jennen D. Embracing the Dark Side: Computational Approaches to Unveil the Functionality of Genes Lacking Biological Annotation in Drug-Induced Liver Injury. Front Genet, 2018; 9:527 . PMID: 30515189 . DOI: 10.3389/ fgene. 2018.00527.

2018

Original articles in indexed journals - Integrative Biomedical Informatics

Speck-Planche A, Scotti MT. BET bromodomain inhibitors: fragment-based in silico design using multi-target QSAR models. Mol Divers, 2018; 23(3): 555-572. PMID: 30421269 . DOI: 10.1007/s11030-018-9890-8.

2018

Original articles in indexed journals - Integrative Biomedical Informatics - PharmacoInformatics

Pastor M, Quintana J, Sanz F. Development of an Infrastructure for the Prediction of Biological Endpoints in Industrial Environments. Lessons Learned at the eTOX Project. Front Pharmacol, 2018; 9: 1147. PMID: 30364191 . DOI: 10.3389/fphar.2018.01147.

2018

Original articles in indexed journals - Integrative Biomedical Informatics

Piñero J, Furlong LI, Sanz F. In silico models in drug development: where we are. Curr Opin Pharmacol, 2018; 42: 111-121.. PMID: 30205360 . DOI: 10.1016/j.coph.2018.08.007.

2018