Original articles in indexed journals - Integrative Biomedical Informatics - PharmacoInformatics - Computational Science - GPCR Drug Discovery

Marti-Solano M, Iglesias A, de Fabritiis G, Sanz F, Brea J, Loza MI, Pastor M, Selent J. Detection of New Biased Agonists for the Serotonin 5-HT2A Receptor: Modeling and Experimental Validation. Mol Pharmacol, 2015; 87 (4): 740-746 . PMID: 25661038 . DOI: 10.1124/mol.114.097022.

2015

Original articles in indexed journals - Integrative Biomedical Informatics - PharmacoInformatics - GPCR Drug Discovery

Martí-Solano M, Sanz F, Pastor M, Selent J. A dynamic view of molecular switch behavior at serotonin receptors: implications for functional selectivity. PLoS One, 2014; 9(10): e109312 . PMID: 25313636 . DOI: 10.1371/journal.pone.0109312.

2014

Original articles in indexed journals - GPCR Drug Discovery

Magnani F, Pappas C, Crook T, Magafa V, Cordopatis P, Ishiguro S, Ohta N, Selent J, Bosnyak S, Jones ES, Gerothanassis I, Tamura M, Widdop ER, Tzakos AG. Sculpting GPCR peptide-ligand subtype selectivity: tackling cancer via a novel drug target. Journal of Peptide Science, 2014; 20 S40-S41

2014

Original articles in indexed journals - PharmacoInformatics - GPCR Drug Discovery

Gonzalez RAD, Silva AG, Guillen EM, McCormick PJ, Solano MM, Torres MIC, Maeso MP, Garcia MIL, Selent J, Perez MC. Investigation of the dimerization interface of the serotonin 5-ht2a receptor by computational and experimental. approaches. Basic & Clinical pharmacology & toxicology, 2014; 115; 49-49; 2 SI70

2014

Original articles in indexed journals - GPCR Drug Discovery

Guixa-Gonzalez R, Javanainen M, Martinez-Seara H, Gomez-Soler M, Domingo JC, Vattulainen I, Ciruela F, Selent J. Cell Membrane Composition Affects GPCR Aggregation. Biophys J, 2014; 106 (2):517A-518A: Sup 1

2014

Original articles in indexed journals - GPCR Drug Discovery

Magnani F, Pappas CG, Crook T, Magafa V, Cordopatis P, Ishiguro S, Ohta N, Selent J, Bosnyak S, Jones ES, Gerothanassis IP, Tamura M, Widdop RE, Tzakos AG. Electronic Sculpting of Ligand-GPCR Subtype Selectivity: The Case of Angiotensin II. ACS Chem Biol, 2014; 9 (7):1420-1425 DOI: 10.1021/cb500063y JUL 2014.

2014

Original articles in indexed journals - GPCR Drug Discovery

Kaczor AA, Makarska-Bialokoz M, Selent J, de la Fuente R, Martí-Solano M, Castro M. Application of BRET for Studying G Protein-Coupled Receptors. Mini-Rev Med Chem, 2014; 14 (5): 411-425 . PMID: 24766382 .

2014

Original articles in indexed journals - GPCR Drug Discovery

Guixa-Gonzalez R, Rodriguez-Espigares I, Ramirez-Anguita JM, Carrio-Gaspar P, Martinez-Seara H, Giorgino T, Selent J. MEMBPLUGIN: studying membrane complexity in VMD. Bioinformatics, 2014; 30; 10: 1478-80 DOI: 10.1093/bioinformatics/btu037.

2014

Original articles in indexed journals - Integrative Biomedical Informatics - PharmacoInformatics - GPCR Drug Discovery

Selent J, Marti-Solano M, Rodríguez J, Atanes P, Brea J, Castro M, Sanz F, Loza MI, Pastor M. Novel insights on the structural determinants of clozapine and olanzapine multi-target binding profiles. Eur J Med Chem, 2014; 77C: 91-95 . PMID: 24631727 . DOI: 10.1016/j.ejmech.2014.02.058 APR 2014.

2014

Original articles in indexed journals - Integrative Biomedical Informatics - PharmacoInformatics - GPCR Drug Discovery

Martí-Solano M, Guixà-González R, Sanz F, Pastor M, Selent J. Novel Insights into Biased Agonism at G Protein-Coupled Receptors and their Potential for Drug Design. Curr Pharm Design, 2013; 19 (28): 5156-5166 . PMID: 23621547 .

2013