Tools
Thursday, 8th March, 2012, Friday, March 9th 2012; 11:00-12:00,
May the force be with you: Biomolecular Nanomachines and the Dynasome
Proteins are biological nanomachines. Virtually every function in the cell is carried out by proteins – ranging from protein synthesis, ATP synthesis, molecular binding and recognition, selective transport, sensor functions, mechanical stability, and many more. The combined interdisciplinary efforts of the past years have revealed how many of these functions are effected on the molecular level. Computer simulations of the atomistic dynamics play a pivotal role in this enterprise, as they offer both unparalleled temporal and special resolution. With state of the art examples, this talk will the type of questions that can (and cannot) be addressed, its (current) limitations, and how these can be overcome. The examples include aquaporin selectivity, mechanics of F-ATP synthase, flexible recognition by nuclear pore transporters, the mechanical properties of viral capsids, and tRNA translocation through the ribosome."
Speaker: Helmut Grübmuller, Max-Planck Institute, Goettingen, Germany
Room Xipre (seminar 173.06-183.01)
