Sunday, 3rd October, 2010, 11h - 12h

Multiscale modelling and simulation, lessons learned from COAST (workshop on multiscale simulations - 2nd Barcelona School on Biomedical Informatics)

A few years ago, within the COAST project, we started to develop a multiscale model of a challenging VPH application, namely in-stent restenosis (ISR). This resulted in a multiscale modelling paradigm that we coined Complex Automata (CxA). CxA models can be implemented using our Multiscale Coupling Library and Environment (MUSCLE). I will introduce the main ideas behind CxA, propose a taxonomy of multiscale models, and try to indicate the lessons learned for VPH type of applications. Multiscale modelling is one thing, but actually executing your multiscale models on computers is quite another ball game. I will show the example of a MUSCLE implementation of a simplified multiscale model for in-stent restenosis. Tightly coupled three dimensional multiscale models will usually require computing power beyond the desktop. This gave rise to the paradigm of Distributed Multiscale Computing, which is currently under development in the MAPPER project.

Speaker: Alfons Hoekstra (University of Amsterdam)

Room PRBB Auditorium