ProfileSeq is a computational method for the quantitative assessment of biological profiles to provide an exact, nonparametric probability that specific regions of the test profile have higher or lower signal densities than a control set. The method is applicable to high-throughput sequencing data (ChIP-Seq, GRO-Seq, CLIP-Seq, etc.) and to genome-based datasets (motifs, etc.). Developed by the Computational RNA Biology group.

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