Thursday, 9th May, 2019, 12.00

ResMarkerDB: a database of biomarkers of response to antibody therapy in breast and colorectal cancer

The clinical efficacy of therapeutic monoclonal antibodies for breast and colorectal cancer has greatly contributed to the improvement of patients' outcomes by individualizing their treatments. However, primary or acquired resistance may occur. Although several databases characterize biomarkers of drug response, there is a need of resources that offer this information to the user in a harmonized manner to support research and development of new alternative treatments. ResMarkerDB was developed as a comprehensive resource of biomarkers of drug response in breast and colorectal cancer. It integrates these data from existing repositories, and new data extracted and curated from the literature (referred as ResCur). It provides a user-friendly web interface (http://www.resmarkerdb.org) to facilitate the exploration of current knowledge of biomarkers of response in breast and colorectal cancer. The database contains more than 500 biomarker-drug-tumour associations. ResMarkerDB aims to enhance translational research efforts in identifying actionable biomarkers of drug response in cancer.

Speaker: Judith Pérez, Integrative Biomedical Informatics - Research Programme on Biomedical Informatics (GRIB, IMIM/UPF)

Room Aula 473.10 (PRBB, 4th floor)