GRIB. Research Unit on Biomedical Informatics





News & activities

Tret de sortida al Projecte europeu ESCAPE-NET

Avui comença a Amsterdam el kick-off meeting del projecte ESCAPE-NET: European Sudden Cardiac Arrest network: towards Prevention, Education and New Treatment, un projecte del programa Horizon 2020 de la Unió Europea, de l'àrea de Medicina Personalitzada. El projecte està coordinat per l'Academisch Medisch Centrum de la Universitat d' Amsterdam i hi participen un total de 16 equips científics de tot Europa, entre ells el grup de recerca en Farmacologia de Sistemes del GRIB (IMIM-UPF) coordinat pel Dr. Jordi Mestres. Aquest grup aportarà al projecte la seva experiència i expertesa en el camp de la predicció del mecanisme d'acció i la seguretat de fàrmacs i participarà en el desenvolupament d'una puntuació de risc d'aturada cardíaca sobtada personalitzada a partir de l'anàlisi individual de quimio i biomarcadors associats a l'arítmia cardíaca.

More info...

Babita Singh, winner of the "Best Science Poster" prize at the IV Bioinformatics and Genomics Symposium

Congratulations to Babita Singh, for the Best Science Poster prize at the IV Bioinformatics and Genomics Symposium held in Barcelona last December.   

Babita is a predoctoral researcher at the Computational RNA Biology group of GRIB (UPF-IMIM) led by Eduardo Eyras. The poster, entitled "Landscape of Somatic Mutations in RNA Splicing Regulatory Elements in Cancer" was selected through participants voting and presents the second chapter of the Babita´s thesis about cis component of alternative splicing in cancer i.e. mutations on regulatory regions that could potentially result to differential splicing. For this purpose it is used the whole genome sequencing data obtained from The Cancer Genome Atlas (TCGA) for 13 different cancer types using ~17million mutations. 

The IV Bioinformatics and Genomics Symposium took place at the Parc de Recerca Biomèdica de Barcelona (PRBB) on the 20th of December of 2016. This symposium was organized together by the Section of Computational Biology and Bioinformatics and the Section of Genomics and Proteomics of the Societat Catalana de Biologia (SCB) and the Bioinformatics Barcelona Association (BIB) and nearly 300 participants attended the symposium. 

For more information and Poster link click here

More info...

More news RSS

Last project

EU-ToxRisk

EU-ToxRisk: "an integrated european 'flagship' program driving mechanism-based toxicity testing and risk assessment for the 21st century" is a H2020 supported collaborative project for the period 2016-2021 in which academia joins forces with small and medium-sized enterprises (SMEs), large industry, contract research organisations (CROs) and regulatory bodies to achieve a paradigm shift in toxicology towards a more efficient and animal-free chemical safety assessment. 

http://www.eu-toxrisk.eu/

More projects

Last publications

  • Piñero J, Bravo A, Queralt-Rosinach N, Gutierrez-Sacristan A, Deu-Pons J, Centeno E, Garcia-Garcıa J, Sanz F, Furlong LI. DisGeNET: a comprehensive platform integrating information on human disease-associated genes and variants. Nucleic Acids Research, 2017; 45: D833-D839. PMID: 27924018 . DOI: 10.1093/nar/gkw943.
  • Roberto G, Leal I, Sattar N, Stewart R, Garcia-Gil M, Avillach P, Egger P, van Wijngaarden R, Ansell D, Reisberg S, Pasqua A, Pedersen L, Tramontan L, Mayer MA, Duarte T, Herings R, Coloma P, Lapi F, Sturkenboom M, van der Lei J, Schuemie M, Rijnbeek P, Gini R. Standardizing Diversity of Event Definitions in Federated Networks of Heterogeneous Health Data Sources: The "Component Algorithm Strategy". Pharmacoepidem DR S, 2016; 25: 165-166; S3
  • Abascal F, Corvelo A, Cruz F, Villanueva-Cañas JL, Vlasova A, Marcet-Houben M, Martínez-Cruz B, Cheng JY, Prieto P, Quesada V, Quilez J, Li G10, García F, Rubio-Camarillo M, Frias L, Ribeca P, Capella-Gutiérrez S, Rodríguez JM, Câmara F, Lowy E, Cozzuto L, Erb I, Tress ML, Rodriguez-Ales JL, Ruiz-Orera J, Reverter F, Casas-Marce M, Soriano L, Arango JR, Derdak S, Galán B, Blanc J, Gut M, Lorente-Galdos B, Andrés-Nieto M, López-Otín C, Valencia A, Gut I, García JL, Guigó R, Murphy WJ, Ruiz-Herrera A, Marques-Bonet T, Roma G, Notredame C, Mailund T, Albà MM, Gabaldón T, Alioto T, Godoy JA. Extreme genomic erosion after recurrent demographic bottlenecks in the highly endangered Iberian lynx. Genome Biol, 2016; 14; 17(1): 251. PMID: 27964752 . DOI: 10.1186/s13059-016-1090-1.
  • Llorian M, Gooding C, Bellora N, Hallegger M, Buckroyd A, Wang X, Rajgor D, Kayikci M, Feltham J, Ule J, Eyras E, Smith CWJ. The alternative splicing program of differentiated smooth muscle cells involves concerted non-productive splicing of post-transcriptional regulators. Nucleic Acids Res, 2016; 44 (18): 8933-8950. PMID: 27317697 . DOI: 10.1093/nar/gkw560 OCT 14 2016.

More publications



Site Information