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FAIRplus sets out to improve data sharing and reuse in life science research

The FAIRplus project has kicked-off to improve data management and data governance in European health research. The project aims to increase the discovery, accessibility and reusability of data from selected projects funded by the EU's Innovative Medicine Initiative (IMI), and internal data from pharmaceutical industry partners. It will also organise training for data scientists in academia, SMEs and pharmaceutical companies to enable wider adoption of best practises in life science data management.

Janssen Pharmaceutica NV is the pharmaceutical industry lead of the project with coordination provided by ELIXIR.  The project involves 22 pharmaceutical, small company and academic partners from nine European countries. It is funded by the IMI as a public-private partnership and will run for three and a half years (2019-2022). European countries. It is funded by the IMI as a public-private partnership and will run for three and a half years (2019-2022). The Integrative Biomedical Informatics group of GRIB (IMIMUPF) led by Laura I. Furlong and Ferran Sanz participates on this project and the main tasks foreseen are the interface with IMI projects in which we are involved (Open PHACTS, eTOX, eTRANSAFE, iPiE, EMIF), the involvement in the definition of the FAIRification processes of data in the following domains: preclinical toxicology, human safety, clinical data, drug impact in the environment, gene-disease associations and the organisation of events and other dissemination activities.

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The Vision of the eTRANSAFE Translational Safety Assessment

First year of the european project eTRANSAFE: read the keynote from Prof. Ferran Sanz, Project Coordinator

The eTRANSAFE project aims at enhancing the efficiency of translational safety assessment during the drug discovery and development process by means of the development of an integrative data infrastructure and innovative computational methods and tools. This infrastructure will be underpinned by legacy data sharing, the use of data standards, such as the SEND format for preclinical studies, and the implementation of a modular computational architecture.

eTRANSAFE started its journey in September 2017 and during the first year, we have set the foundations for the development of widely accepted guidelines on safe legacy data sharing, and we have been working in the extension of the preclinical database released in the previous IMI eTOX project, in terms of incorporation of individual animal data in SEND format together with structural and pharmacological information. In addition, identification of useful data available in the public domain, its integration with the data contributed from the EFPIA partners and the identification of potential challenges by means of prototypes and use cases have been the first steps to move forward the development of the eTRANSAFE Knowledge Hub.

The Project is pleased of the progress achieved and will continue advancing towards the final objective of supporting and improving the drug discovery and development.

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FAIRPlus

The project FAIRPlus aims to improve data management and data governance in European health research. The project aims to increase the discovery, accessibility and reusability of data from selected projects funded by the EU's Innovative Medicine Initiative (IMI), and internal data from pharmaceutical industry partners. It will also organise training for data scientists in academia, SMEs and pharmaceutical companies to enable wider adoption of best practises in life science data management. The project is funded by the Innovative Medicines Initiative (IMI2) together with the pharmaceutical industry for the period 2019-2021.

https://fairplus-project.eu/

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