Researchers of the Evolutionary Genomics group of GRIB (IMIM-UPF) and the Universitat Politècnica de Catalunya (UPC) have recently published a study in eLife showing that RNA called non-coding (IncRNA) plays an important role in the evolution of new proteins, some of which could have important cell functions yet to be discovered.
“We have confirmed that in all six species that were studied –human beings, mice, fish, flies, yeast and a plant– many of the IncRNAs were associated to ribosomes and seemed to be ready to translate RNA into proteins. This suggests that they could act as a repository for the synthesis of new proteins” explains Mar Albà, ICREA professor and leader of the Evolutionary Genomics grup.
Article Ref.: Ruiz-Orera J, Messeguer X, Subirana JA, Alba MM. Long non-coding RNAs as a source of new peptides. eLife, 2014;3: e03523
Click here to have a look to the interview to Magda Gayà-Vidal, a former student of GRIB, talking about the results obtained in her master thesis carried out in the Evolutionary Genomics group, which has been recently published.
Apart from talking about the most interesting results of that study (the identification of ~200 genes that have evolved more rapidly in humans than in other primates), it was also the opportunity to talk about research in genetics in plain language.
Article ref.: Gayà-Vidal M & Albà MM (2014). Uncovering adaptive evolution in the human lineage. BMC Genomics 15:599.
The Open Pharmacological Concepts Triple Store project (Open PHACTS) will develop an open access innovation platform, called Open Pharmacological Space (OPS), via a semantic web approach. OPS will be comprised of data, vocabularies and infrastructure needed to accelerate drug- oriented research. The aim is to develop an enabling resource for drug discovery projects which is open to all users and freely available in the public domain. This european project is funded by IMI and has been recently extended until 2016.