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Results 1 - 10 of about 62
Original articles in indexed journals - GPCR Drug Discovery
Jaiteh M, Rodríguez-Espigares I, Selent J, Carlsson J. Performance of virtual screening against GPCR homology models: Impact of template selection and treatment of binding site plasticity. PLoS Comput Biol, 2020; 16(3): e1007680. PMID: 32168319 . DOI: 10.1371/journal.pcbi.1007680.
2020
PhD Thesis - GPCR Drug Discovery
Stępniewski T. Unraveling the complex signaling behavior of neurotransmitters and their receptors in the brain. Universitat Pompeu Fabra. January, 9th 2020. Thesis Director: Selent J.
2020
Original articles in indexed journals - Computational Science - GPCR Drug Discovery
Rodríguez-Espigares I, Torrens-Fontanals M, Tiemann JKS at al (including De Fabritiis G and Selent J). GPCRmd uncovers the dynamics of the 3D-GPCRome. bioRxiv, 2019; 839597 DOI: 10.1101/839597.
2019
Garcia Silva A, Marti Solano M, Selent J, Loza Garcia M, Castro Perez M. Quantification of functional bias of serotonin 5-HT2A receptor agonists and validation of structural hypotheses on functional selectivity at 5-HT2A receptor. BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY 125, 44-44 2019
2019
Original articles in indexed journals - GPCR Drug Discovery
Ghosh E, Dwivedi H, Baidya M, Srivastava A, Kumari P, Stepniewski T, Kim HR, Lee MH, van Gastel J, Chaturvedi M, Roy D, Pandey S, Maharana J, Guixà-González R, Luttrell LM, Chung KY, Dutta S, Selent J, Shukla AK. Conformational Sensors and Domain Swapping Reveal Structural and Functional Differences between β-Arrestin Isoforms. Cell Rep 2019; 28(13): 3287-3299.e6. PMID: 31553900 . DOI: 10.1016/j.celrep.2019.08.053.
2019
Original articles in indexed journals - GPCR Drug Discovery
Abraham MJ, Apostolov RP, Barnoud J, Bauer P, Blau C, Bonvin AMJJ, Chavent M, Chodera JD, Condic-Jurkic K, Delemotte L, Grubmüller H, Howard RJ, Jordan EJ, Lindal E, Ollila OHS, Selent J, Smith DGA, Stansfeld PJ, Tiemann JKS, Trellet M, Woods CJ, Zhmurov A. Sharing Data from Molecular Simulations. J Chem Inf Model. 2019. PMID: 31525920 . DOI: 10.1021/acs.jcim.9b00665.
2019
Original articles in indexed journals - GPCR Drug Discovery
Karoussiotis C, Martí-Solano M, Stepniewski T, Symeonof A, Selent J, Georgoussi Z. A highly conserved δ‐opioid receptor region determines RGS4 interaction. FEBS J, 2019. PMID: 31386272 . DOI: 10.1111/febs.15033.
2019
Original articles in indexed journals - GPCR Drug Discovery
M Baidya, P Kumari, H Dwivedi, E Ghosh, B Sokrat, S Sposini, S Pandey et al (including Stepniewski T and Selent J). Genetically encoded intrabody sensors illuminate structural and functional diversity in GPCR-β-arrestin complexes. bioRxiv, 2019; 651463 DOI: 10.1101/651463.
2019
Original articles in indexed journals - GPCR Drug Discovery
Sánchez-Melgar A, Albasanz JL*, Guixà-González R, Saleh N, Selent J, Martín M. The antioxidant resveratrol acts as a non-selective adenosine receptor agonist. Free Radical Biol Med, 2019; 135: 261-273.. PMID: 30898665 . DOI: 10.1016/j.freeradbiomed.2019.03.019.
2019
Original articles in indexed journals - GPCR Drug Discovery
Stepniewski TM, Torrens-Fontanals M, Rodríguez – Espigares I, Giorgino T, Primdahl KG, Vik A, Stenstrøm Y, Selent J, Hansen TV. Synthesis, molecular modelling studies and biological evaluation of new oxoeicosanoid receptor 1 agonists. Bioorgan Med Chem, 2018; 26, 12: 3580-3587. PMID: 29866479 . DOI: 10.1016/j.bmc.2018.05.036.
2018
