Original articles in indexed journals - GPCR Drug Discovery

Rodríguez-Espigares I, Giorgino T, Primdahl KG, Vik A, Stenstrøm Y, Selent J, Hansen TV. Synthesis, molecular modelling studies and biological evaluation of new oxoeicosanoid receptor 1 agonists. Bioorgan Med Chem, 2018; pii: S0968-0896(18)30256-6. PMID: 29866479 . DOI: 10.1016/j.bmc.2018.05.036.

2018

PhD Thesis - GPCR Drug Discovery

Rodríguez Espigares, I. GPCRmd - A web platform for collection, visualization and analysis of molecular dynamics data for G protein-coupled receptors. Universitat Pompeu Fabra.  April 4th, 2018. Thesis Directors: Sanz F and Selent J.

2018

Original articles in indexed journals - GPCR Drug Discovery

Kaczor AA, Bartuzi D, Stepniewski TM, Matosiuk D, Selent J. Protein-Protein Docking in Drug Design and Discovery. Methods Mol Biol, 2018; 1762:285-305. PMID: 29594778 . DOI: 10.1007/978-1-4939-7756-7_15.

2018

Original articles in indexed journals - GPCR Drug Discovery

Ramírez-Anguita JM, Rodríguez-Espigares I, Guixà-González R, Bruno A, Varela-Rial A, Selent J. Membrane cholesterol effect on the 5-HT2A receptor: Insights into the lipid-induced modulation of an antipsychotic drug target. Biotechnol Appl Bioc, 2017 . PMID: 28877377 . DOI: 10.1002/bab.1608.

2017

Original articles in indexed journals - GPCR Drug Discovery

Iglesias A, Cimadevila M, la Fuente RA, Martí-Solano M, Cadavid MI, Cadavid MI, Selent J, Loza MI, Brea J. Serotonin 2A receptor disulfide bridge integrity is crucial for ligand binding to different signalling states but not for its homodimerization. Eur J Pharmacol, 2017 . PMID: 28899696 . DOI: 10.1016/j.ejphar.2017.09.011.

2017

Original articles in indexed journals - GPCR Drug Discovery

Azuaje J, López P, Iglesias A, de la Fuente RA, Pérez-Rubio JM, García D, Stępniewski TM, García-Mera X, Brea JM, Selent J, Pérez D, Castro M, Loza MI, Sotelo E. Development of Fluorescent Probes that Target Serotonin 5-HT2B Receptors. Sci Rep, 2017; 7 (1): 10765 . PMID: 28883627 . DOI: 10.1038/s41598-017-11370-2.

2017

Original articles in indexed journals - GPCR Drug Discovery

Oddi S, Totaro A, Scipioni L, Dufrusine B, Stepniewski TM, Selent J, Maccarrone M, Dainese E. Role of palmitoylation of cysteine 415 in functional coupling CB1 receptor to Gαi2 protein. Biotechnol Appl Bioc, 2017 . PMID: 28722168 . DOI: 10.1002/bab.1575.

2017

Original articles in indexed journals - Integrative Biomedical Informatics - PharmacoInformatics - GPCR Drug Discovery

Guixà-González R, Albasanz JL, Rodríguez-Espigares I, Pastor M, Sanz F, Martí-Solano M, Manna M, Martínez-Seara H, Hildebrand PW, Martí M, Selent J. Membrane cholesterol access into a G-protein-coupled receptor. Nat Commun, 2017; 8: 14505 . PMID: 28220900 . DOI: 10.1038/ncomms14505.

2017

Original articles in indexed journals - GPCR Drug Discovery

Lally CCM, Bauer B, Selent J, Sommer ME. C-edge loops of arrestin function as a membrane anchor. Nature Commun, 2017; 8: 14258 . PMID: 28220785 . DOI: 10.1038/ncomms14258.

2017

Original articles in indexed journals - GPCR Drug Discovery

Oddi S, Stepniewski TM, Totaro A, Selent J, Scipioni L, Dufrusine B, Fezza F, Dainese E, Maccarrone M. Palmitoylation of cysteine 415 of CB₁ receptor affects ligand-stimulated internalization and selective interaction with membrane cholesterol and caveolin 1. Biochim Biophys Acta, 2017;  1862 (5): 523-532 . PMID: 28215712 . DOI: 10.1016/j.bbalip.2017.02.004.

2017