Original articles in indexed journals - Computational Science

Ferruz N, De Fabritiis. GBinding Kinetics in Drug Discovery. Mol Inf, 2016; 35 (6-7):216-226 DOI: 10.1002/minf.201501018.

2016

Original articles in indexed journals - GPCR Drug Discovery

Rodriguez-Espigares I, Kaczor AA, Selent J. In silico Exploration of the Conformational Universe of GPCRs. Mol Inf, 2016; 35 (6-7):227-237 . PMID: 27492237 . DOI: 10.1002/minf.201600012.

2016

Original articles in indexed journals - Structural Bioinformatics

Sieberts SK, Zhu F, García-García J, Stahl E, Pratap A, Pandey G, Pappas D, Aguilar D, Anton B, Bonet J, Eksi R, Fornés O, Guney E, Li H, Marín MA, Panwar B, Planas-Iglesias J, Poglayen D, Cui J, Falcao AO et al (including Oliva B). Crowdsourced assessment of common genetic contribution to predicting anti-TNF treatment response in rheumatoid arthritis. Nature Commun, 2016; 7: 12460 . PMID: 27549343 . DOI: doi:10.1038/ncomms12460.

2016

Original articles in indexed journals - Computational RNA Biology

Trincado JL, Sebestyen E, Pages A, Eyras E. The prognostic potential of alternative transcript isoforms across human tumors. Genome Med, 2016; 8 (1): 85 . PMID: 27535130 . DOI: 10.1186/s13073-016-0339-3 AUG 17 2016.

2016

Original articles in indexed journals - Integrative Biomedical Informatics

Roberto G, Leal I, Sattar N, Loomis AK, Avillach P, Egger P, van Wijngaarden R, Ansell D, Reisberg S, Tammesoo ML, Alavere H, Pasqua A, Pedersen L, Cunningham J, Tramontan L, Mayer MA, Herings R, Coloma P, Lapi F, Sturkenboom M, van der Lei J, Schuemie MJ, Rijnbeek P, Gini R. Identifying Cases of Type 2 Diabetes in Heterogeneous Data Sources: Strategy from the EMIF Project. PLoS ONE 2016; 11(8): e0160648 . PMID: 27580049 . DOI: 10.1371/journal.pone.0160648.

2016

Original articles in indexed journals - Computational RNA Biology

Martin S, Bellora N, González-Vallinas J, Irimia M, Chebli K, DeToledo M, Raabe M, Eyras E, Urlaub H, Blencowe BJ, Tazi J. Preferential Binding of a stable G3BP Ribonucleoprotein Complex to Intron-retaining Transcripts in Mouse Brain and Modulation of their Expression in the Cerebellum. J Neurochem, 2016; . PMID: 27513819 . DOI: 10.1111/jnc.13768.

2016

Original articles in indexed journals - Integrative Biomedical Informatics

Queralt-Rosinach N, Piñero J, Bravo A, Sanz F, Furlong LI. DisGeNET-RDF: Harnessing the Innovative Power of the Semantic Web to Explore the Genetic Basis of Diseases. Bioinformatics, 2016; 32(14): 2236-8 . PMID: 27153650 . DOI: 10.1093/bioinformatics/btw214.

2016

Original articles in indexed journals - Structural Bioinformatics

Poglayen D, Marín-López MA, Bonet J, Fornes O, Garcia-Garcia J, Planas-Iglesias J, Segura J, Oliva B, Fernandez-Fuentes N. InteractoMIX: a suite of computational tools to exploit interactomes in biological and clinical research. Biochem Soc Trans, 2016; 44(3): 917-24 . PMID: 27284060 . DOI: 10.1042/BST20150001.

2016

Original articles in indexed journals - Integrative Biomedical Informatics

Digles D, Zdrazil B, Neefs JM, Van Vlijmen H, Herhaus C, Caracoti A. Brea J, Roibas B, Loza MI, Queralt-Rosinach N, Furlong LI, Gaulton A, Bartek L, Senger S, Chichester C, Engkvist O, Evelo CT, Franklin NI, Marren D, Ecker GF, Jacoby E. Open PHACTS computational protocols for in silico target validation of cellular phenotypic screens: knowing the knowns. MEDCHEMCOMM, 7 (6): 1237-1244 DOI: 10.1039/c6md00065g 2016.

2016

Original articles in indexed journals - Systems Pharmacology

Van Voorhis WC, Adams JH, Adelfio R, Ahyong V, Akabas MH, Alano P, Alday A, Alemán Resto Y, Alsibaee A, Alzualde A, Andrews KT, Avery SV et al (including Mestres J). Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond. PLoS Pathog, 2016; 12(7): e1005763. . PMID: 27467575 . DOI: 10.1371/journal.ppat.1005763. eCollection 2016.

2016