Original articles in indexed journals - Integrative Biomedical Informatics - PharmacoInformatics - GPCR Drug Discovery

Guixà-González R, Albasanz JL, Rodríguez-Espigares I, Pastor M, Sanz F, Martí-Solano M, Manna M, Martínez-Seara H, Hildebrand PW, Martí M, Selent J. Membrane cholesterol access into a G-protein-coupled receptor. Nat Commun, 2017; 8: 14505 . PMID: 28220900 . DOI: 10.1038/ncomms14505.

2017

Original articles in indexed journals - GPCR Drug Discovery

Lally CCM, Bauer B, Selent J, Sommer ME. C-edge loops of arrestin function as a membrane anchor. Nature Commun, 2017; 8: 14258 . PMID: 28220785 . DOI: 10.1038/ncomms14258.

2017

Original articles in indexed journals - GPCR Drug Discovery

Oddi S, Stepniewski TM, Totaro A, Selent J, Scipioni L, Dufrusine B, Fezza F, Dainese E, Maccarrone M. Palmitoylation of cysteine 415 of CB₁ receptor affects ligand-stimulated internalization and selective interaction with membrane cholesterol and caveolin 1. Biochim Biophys Acta, 2017;  1862 (5): 523-532 . PMID: 28215712 . DOI: 10.1016/j.bbalip.2017.02.004.

2017

Original articles in indexed journals - Integrative Biomedical Informatics - Structural Bioinformatics

Piñero J, Bravo A, Queralt-Rosinach N, Gutierrez-Sacristan A, Deu-Pons J, Centeno E, Garcia-Garcıa J, Sanz F, Furlong LI. DisGeNET: a comprehensive platform integrating information on human disease-associated genes and variants. Nucleic Acids Research, 2017; 45: D833-D839 . PMID: 27924018 . DOI: 10.1093/nar/gkw943.

2017

Original articles in indexed journals - Evolutionary Genomics

Domazet-Loso T, Carvunis AR, Alba MM, Sestak MS, Bakaric R, Neme R, Tautz D. No evidence for phylostratigraphic bias impacting inferences on patterns of gene emergence and evolution. Mol Biol Evol, 2017; 34 (4): 843-856 . PMID: 28087778 . DOI: 10.1093/molbev/msw284 APR 2017.

2017

Original articles in indexed journals - Integrative Biomedical Informatics

Gutiérrez-Sacristán A, Bravo A, Portero-Tresserra M, Valverde O, Armario A, Blanco-Gandía MC, Farré A, Fernández-Ibarrondo L, Fonseca F, Giraldo J, Leis A, Mané A, Mayer MA, Montagud-Romero S, Nadal R, Ortiz J, Pavon FJ, Perez EJ, Rodríguez-Arias M, Serrano A, Torrens M, Warnault V, Sanz F, Furlong LI. Text mining and expert curation to develop a database on psychiatric diseases and their genes. Database (Oxford), 2017; 2017: bax043.. PMID: 29220439 . DOI: 10.1093/database/bax043.

2017

Original articles in indexed journals - GPCR Drug Discovery

Rodríguez-Espigares I, Kaczor AA, Stepniewski TM, Selent J. Challenges and Opportunities in Drug Discovery of Biased Ligands. Methods Mol Biol, 2017; 1705: 321-334 . PMID: 29188569 . DOI: 10.1007/978-1-4939-7465-8_14.

2017

Original articles in indexed journals - Computational Science

Martínez-Rosell G, Giorgino T, De Fabritiis G. PlayMolecule ProteinPrepare: A Web Application for Protein Preparation for Molecular Dynamics Simulations. J Chem Inf Model, 2017; 57 (7): 1511–1516. PMID: 28594549 . DOI: 10.1021/acs.jcim.7b00190.

2017

Original articles in indexed journals - Computational RNA Biology

Llorian M, Gooding C, Bellora N, Hallegger M, Buckroyd A, Wang X, Rajgor D, Kayikci M, Feltham J, Ule J, Eyras E, Smith CWJ. The alternative splicing program of differentiated smooth muscle cells involves concerted non-productive splicing of post-transcriptional regulators. Nucleic Acids Res, 2016; 44 (18): 8933-8950 . PMID: 27317697 . DOI: 10.1093/nar/gkw560 OCT 14 2016.

2016

Original articles in indexed journals - Evolutionary Genomics

Abascal F, Corvelo A, Cruz F, Villanueva-Cañas JL, Vlasova A, Marcet-Houben M, Martínez-Cruz B, Cheng JY, Prieto P, Quesada V, Quilez J, Li G10, García F, Rubio-Camarillo M, Frias L, Ribeca P, Capella-Gutiérrez S, Rodríguez JM, Câmara F, Lowy E, Cozzuto L, Erb I, Tress ML, Rodriguez-Ales JL, Ruiz-Orera J, Reverter F, Casas-Marce M, Soriano L, Arango JR, Derdak S, Galán B, Blanc J, Gut M, Lorente-Galdos B, Andrés-Nieto M, López-Otín C, Valencia A, Gut I, García JL, Guigó R, Murphy WJ, Ruiz-Herrera A, Marques-Bonet T, Roma G, Notredame C, Mailund T, Alba MM, Gabaldón T, Alioto T, Godoy JA. Extreme genomic erosion after recurrent demographic bottlenecks in the highly endangered Iberian lynx. Genome Biol, 2016; 14; 17(1): 251 . PMID: 27964752 . DOI: 10.1186/s13059-016-1090-1.

2016