Original articles in indexed journals - GPCR Drug Discovery

Giubilaro J, Schuetz DA, Stepniewski T, Namkung Y, Khoury E, Lara-Márquez M, Campbell S, Beautrait A, Armando S, Radresa O, Duchaine J, Lamarche-Vane N, Claing A, Selent J, Bouvier M, Marinier A, Laporte SA*. Discovery of a dual Ras and ARF6 inhibitor from a GPCR endocytosis screen. Nat Commun 2021; 12(1): 4688. PMID: 34344896 . DOI: 10.1038/s41467-021-24968-y.

2021

Original articles in indexed journals - Integrative Biomedical Informatics

Aerts H, Kalra D, Sáez C, Ramírez-Anguita JM, Mayer MA, Garcia-Gomez JM, Durà-Hernández M, Thienpont G, Coorevits P. Quality of Hospital Electronic Health Record (EHR) Data Based on the International Consortium for Health Outcomes Measurement (ICHOM) in Heart Failure: Pilot Data Quality Assessment Study. JMIR Med Inform, 2021; 4; 9(8): e27842. PMID: 34346902 . DOI: 10.2196/27842.

2021

Original articles in indexed journals - Systems Pharmacology

Falaguera MJ, Mestres J. Congenericity of Claimed Compounds in Patent Applications. Molecules, 2021; 30;26(17): 5253. PMID: 34500686 . DOI: 10.3390/molecules26175253.

2021

Original articles in indexed journals - GPCR Drug Discovery

Stepniewski TM, Mancini A, Agren R, Torrens-Fontanals M, M Semache, Bouvier M, Sahlholm K, Breton B, Selent J . Mechanistic insights into dopaminergic and serotonergic neurotransmission-concerted interactions with helices 5 and 6 drive the functional outcome. Chem Sci, 2021; 2; 12(33): 10990-11003.. PMID: 34522296 . DOI: 10.1039/D1SC00749A.

2021

Original articles in indexed journals - NeuroGenomics

Taylor SR, Santpere G, Weinreb A, Barrett A, Reilly MB, Xu C, Varol E, Oikonomou P, Glenwinkel L, McWhirter R, Poff A, Basavaraju M, Rafi I, Yemini E, Cook SJ, Abrams A, Vidal B, Cros C, Tavazoie S, Sestan N, Hammarlund M, Hobert O, Miller DM 3rd. Molecular topography of an entire nervous system. Cell, 2021; S0092-8674(21)00758-3. PMID: 34237253 . DOI: 10.1016/j.cell.2021.06.023.

2021

Original articles in indexed journals - GPCR Drug Discovery

Kumar GA, Sarkar P, Stepniewski T, Jafurulla M, Singh SP, Selent J*, Chattopadhyay A*. A molecular sensor for cholesterol in the human serotonin 1A receptor. Sci Adv 2021; 7(30): eabh2922. PMID: 34301606 . DOI: 10.1126/sciadv.abh2922.

2021

Original articles in indexed journals - Integrative Biomedical Informatics

Real de Asua D, Mayer MA, Ortega MdC, Borrel JM, Bermejo TdJ, González-Lamuño D, Manso C, Moldenhauer F, Carmona-Iragui M, Hüls A, Sherman SL, Strydom A, de la Torre R, Dierssen M on behalf of the Spanish Trisomy 21 Research Society COVID-19 Taskforce. Comparison of COVID-19 and Non-COVID-19 Pneumonia in Down Syndrome. J Clin Med, 2021; 10(16): 3748 . PMID: 34442043 . DOI: 10.3390/jcm101637.

2021

Original articles in indexed journals - Computational RNA Biology

Yuen ZW, Srivastava A, Daniel R, McNevin D, Jack C, Eyras E. Systematic benchmarking of tools for CpG methylation detection from nanopore sequencing. Nat Commun, 2021; 12(1):3438. PMID: 34103501 . DOI: 10.1038/s41467-021-23778-6.

2021

Original articles in indexed journals - Integrative Biomedical Informatics

Giannoula A, Centeno E, Mayer MA, Sanz F, Furlong LI. A system-level analysis of patient disease trajectories based on clinical, phenotypic and molecular similarities. Bioinformatics, 2021; 37(10):1435-1443.. PMID: 33185649 . DOI: 10.1093/bioinformatics/btaa964.

2021

Original articles in indexed journals - Evolutionary Genomics

Mudge JM, Ruiz-Orera J, Prensner JR, Brunet MA, Gonzalez JM, Magrane M, Martinez T, Schulz JF, Yang YT, Albà MM et al. A community-driven roadmap to advance research on translated open reading frames detected by Ribo-seq. bioRxiv, 2021 DOI: 10.1101/2021.06.10.447896.

2021