Original articles in indexed journals - Integrative Biomedical Informatics - Structural Bioinformatics

Piñero J, Bravo A, Queralt-Rosinach N, Gutierrez-Sacristan A, Deu-Pons J, Centeno E, Garcia-Garcıa J, Sanz F, Furlong LI. DisGeNET: a comprehensive platform integrating information on human disease-associated genes and variants. Nucleic Acids Research, 2017; 45: D833-D839 . PMID: 27924018 . DOI: 10.1093/nar/gkw943.

2017

Original articles in indexed journals

Rubio-Perez C, Deu-Pons J, Tamborero D, Lopez-Bigas N, Gonzalez-Perez A. Rational design of cancer gene panels with OncoPaD. Genome Med, 2016; 8(1):98. PMID: 27716338 .

2016

Original articles in indexed journals

Iorio F, Knijnenburg TA, Vis DJ, Bignell GR, Menden MP, Schubert M, Aben N, Gonçalves E, Barthorpe S, Lightfoot H, Cokelaer T, Greninger P, van Dyk E, Chang H, de Silva H, Heyn H, Deng X, Egan RK, Liu Q, Mironenko T, Mitropoulos X, Richardson L, Wang J, Zhang T, Moran S, Sayols S, Soleimani M, Tamborero D, Lopez-Bigas N, Ross-Macdonald P, Esteller M, Gray NS, Haber DA, Stratton MR, Benes CH, Wessels LFA, Saez-Rodriguez J, McDermott U, Garnett MJ. A Landscape of Pharmacogenomic Interactions in Cancer. Cell, 2016; 166 (3):740-754 . PMID: 27397505 . DOI: 10.1016/j.cell.2016.06.017.

2016

Original articles in indexed journals

Mularoni L, Sabarinathan R, Deu J, González-Pérez A, López-Bigas N. OncodriveFML: a general framework to identify coding and non-coding regions with cancer driver mutations. Genome Biol 2016; 17(1): 128 . PMID: 27311963 . DOI: 10.1186/s13059-016-0994-0.

2016

Original articles in indexed journals

Sabarinathan R, Mularoni L, Deu-Pons J, Gonzalez-Perez A, Lopez-Bigas N. Nucleotide excision repair is impaired by binding of transcription factors to DNA. Nature, 2016; 532 (7598): 264-7 . PMID: 27075101 . DOI: 10.1038/nature17661.

2016

Original articles in indexed journals - Integrative Biomedical Informatics

Piñero J, Berenstein A, Gonzalez-Perez A, Chernomoretz A, Furlong LI. Uncovering disease mechanisms through network biology in the era of Next Generation Sequencing. Sci Rep, 2016; 6: 24570 . PMID: 27080396 . DOI: 10.1038/srep24570.

2016

Original articles in indexed journals

Frigola J, Iturbide A, Lopez-Bigas N, Peiro S, Gonzalez-Perez A. Altered oncomodules underlie chromatin regulatory factors driver mutations. Oncotarget, 2016; 7 (21):30748-30759
  . PMID: 27095575 . DOI: 10.16632/oncotarget.8952 MAY 24 2016.

2016

Original articles in indexed journals

Gonzalez-Perez A. Circuits of cancer drivers revealed by convergent misregulation of transcription factor targets across tumor types. Genome Med, 2016; 8 (1): 6 . PMID: 26792175 . DOI: 10.1186/s13073-015-0260-1..

2016

Original articles in indexed journals - Systems Pharmacology

Rubio-Perez C, Tamborero D, Schroeder MP, Antolin AA, Deu-Pons J, Perez-Llamas C, Mestres J, Gonzalez-Perez A, Lopez-Bigas N. In silico prescription of anticancer drugs to cohorts of 28 tumor types reveals novel targeting opportunities. Cancer Res, 2015; 75 (22): 1 DOI: 10.1158/1538-7445.TRANSCAGEN-A1-45.

2015

Original articles in indexed journals

Puente XS, Beà S, Valdés-Mas R, Villamor N, Gutiérrez-Abril J, Martín-Subero JI, Munar M, Rubio-Pérez C, Jares P, Aymerich M, Baumann T, Beekman R, Belver L, Carrio A, Castellano G, Clot G, Colado E, Colomer D, Costa D, Delgado J, Enjuanes A, Estivill X, Ferrando AA, Gelpí JL, González B, González S, González M, Gut M, Hernández-Rivas JM, López-Guerra M, Martín-García D, Navarro A, Nicolás P, Orozco M, Payer ÁR, Pinyol M, Pisano DG, Puente DA, Queirós AC, Quesada V, Romeo-Casabona CM, Royo C, Royo R, Rozman M, Russiñol N, Salaverría I, Stamatopoulos K, Stunnenberg HG, Tamborero D, Terol MJ, Valencia A, López-Bigas N, Torrents D, Gut I, López-Guillermo A, López-Otín C, Campo E. Non-coding recurrent mutations in chronic lymphocytic leukaemia. Nature, 2015; 526 (7574): 519-U115 . PMID: 26200345 . DOI: 10.1038/nature14666 OCT 22 2015.

2015