GRIB. Research Unit on Biomedical Informatics

News & activities

EU-ToxRisk: an integrated european ‘Flagship’ program driving mechanism-based toxicity testing and risk assessment for the 21st century

In a large (30 Million €) H2020-supported collaborative project, academia joins forces with small and medium-sized enterprises (SMEs), large industry, contract research organisations (CROs) and regulatory bodies to achieve a paradigm shift in toxicology towards a more efficient and animal-free chemical safety assessment.

The Research Programme on Biomedical Informatics, GRIB (UPF-IMIM) will have a major role in this project bringing its expertise in Bioinformatics and Chemoinformatics. In particular, members of GRIB will be responsible of compiling and making available to the rest of the consortium the enabling computational technologies that will play a central role in the project. These include read-across and quantitative structure-activity methods, in silico pharmacokinetics, platforms for the analysis of omics information, and statistical methods for data analysis and visualization. This contributions will be aligned to the role that GRIB is playing in IMI projects focused on the safety assessment of drugs: the eTOX project focused on the in silico prediction of in vivo toxicity, and the iPiE one aiming to assess the ecotoxicological risks of pharmaceuticals.

More info...

Come to the fourth DCEXS Symposium on November the 17th: "Innovative in silico strategies in biomedical research"

The symposium, organized by the Department of Experimental and Health Sciences (DCEXS) and the GRIB (IMIM-UPF) will be held on Tuesday, November 17th 2015, at the Barcelona Biomedical Research Park (PRBB) auditorium and will bring together leading researchers in the vibrant field of biomedical research, to explore new advances in in silico strategies.

Confirmed Speakers: Marta Filizola, Joaquín Dopazo,
Gerhard Ecker, Alfonso Valencia ,  Mihaela Zavolan,
Caroline Gubser Keller

The symposium is open to everybody interested in biomedical research, and there are no registration fees. However, the number of places available are limited so you are kindly asked to register here.

Do you have a poster? Present it at the symposium reception, you can win an iPad! Send an email with your abstract to before the 15th of October.

More info...

More news RSS

Last project


The project MedBioinformatics "Creating medically-driven integrative bioinformatics applications focused on oncology, CNS disorders and their comorbidities" aims to develop useful bioinformatics tools and applications, and autonomously usable for analysing the huge amount of data and knowledge generated in healthcare and biomedical research in order to facilitate translational research and precision medicine. European project funded by H2020 for the period 2015-2018 and coordinated by the GRIB.

More projects

Last publications

  • Subirana JA, Albà MM, Messeguer X. High evolutionary turnover of satellite families in Caenorhabditis. BMC Evol Biol, 2015; 15(1):218. PMID: 26438045 . DOI: 10.1186/s12862-015-0495-x.
  • Zhang RX, Calixto CPG, Tzioutziou NA, James AB, Simpson CG, Guo WB, Marquez Y, Kalyna M, Patro R, Eyras E, Barta A, Nimmo HG, Brown JWS. AtRTD - a comprehensive reference transcript dataset resource foraccurate quantification of transcript-specific expression in Arabidopsis thaliana. New Phitol, 2015; 208 (1): 96-101. PMID: 26111100 . DOI: 10.1111/nph.13545.
  • Resa-Infante P, Paterson D, Bonet J, Otte A, Oliva B, Fodor E, Gabriel G. Targeting importin-alpha 7 as a therapeutic approach against pandemic influenza viruses. J Virol, 2015; 89 (17): 9010-9020 DOI: 10.1128/JVI.00583-15 SEP 2015.
  • Garcia-Serna R, Vidal D, Remez N, Mestres J. Large Scale Predictive Drug Safety: From Structural Alerts to Biological Mechanisms. Chem Res Toxicol, 2015. PMID: 26360911 . DOI: 10.1021/ acs.chemrestox. 5b00260.

More publications

Site Information

Warning: Unknown: 1 result set(s) not freed. Use mysql_free_result to free result sets which were requested using mysql_query() in Unknown on line 0