GRIB. Research Unit on Biomedical Informatics





News & activities

European Medical Information Framework (EMIF) Colloquium - December 10th (18:00 - 20:00) at PRBB auditorium

The Colloquium will allow the EMIF partners, represented by 120 European scientists involved in the project, to explain the importance of real world data and the potential of EMIF in unlocking this information. The audience will consist of local stakeholders, pharmaceutical companies, the research
community and media.
The event will be held on December 10, between 18:00 - 20:00 at the Barcelona Biomedical Research Park (PRBB) auditorium. It will be followed by a networking drink on the PRBB terrace. There will be simultaneous interpretation available. Please register before December the 5th.

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LOD cloud

DisGeNET inclòs en el diagrama Linking Open Data (LOD)

La plataforma per a l’anàlisi de les malalties humanes i els seus gens DisGeNET, desenvolupada pel Grup de recerca en Informàtica Biomèdica Integrativa del GRIB (IMIM-UPF) dirigit per Laura I. Furlong i Ferran Sanz, apareix per primera vegada en el diagrama de vinculació Linking Open Data (LOD).

Aquest tipus de diagrama mostra conjunts de dades en format Linked Data, que utilitza la World Wide Web (Web) per connectar dades estructurades i relacionades. El Linked Data és la millor manera d’exposar, compartir i connectar dades, informació i coneixement a la Web Semàntica.

La presència de DisGeNET en aquest diagrama és important perquè posa de manifest que la base de dades DisGeNET es publica d'acord amb els principis del Linked Data, i fa que sigui més visible i detectable pels usuaris del diagrama.

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Last project

eTOX

Integrating bioinformatics and chemoinformatics approaches for the development of expert systems allowing the in silico prediction of toxicities. European project funded by IMI, extended until 2016 and coordinated by the GRIB. The eTOX project aims to develop a drug safety database from the pharmaceutical industry legacy toxicology reports and public toxicology data, innovative in silico strategies and novel software tools to better predict the toxicological profiles of small molecules in early stages of the drug development pipeline.

http://www.e-tox.net/index.html

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Last publications

  • Dumontier M, Baker CJO, Baran J, Callahan A, Chepelev L, Cruz-Toledo J, Del Rio NR, Duck G, Furlong LI, Keath N, Klassen D, McCusker JP, Queralt-Rosinach N, Samwald M, Villanueva-Rosales N, Wilkinson MD, Hoehndorf R. The Semanticscience Integrated Ontology (SIO) for biomedical research and knowledge discovery. J Biom Sem, 2014; 5:14 DOI: 10.1186/2041-1480-5-14.
  • Antolin A, Mestres J*. Distant Polypharmacology among MLP Chemical Probes. ACS Chem Biol 2014. PMID: 25365788 .
  • Guiu J, Bergen D, De Pater E, Islam A, Ayllón V, Gama-Norton L, Ruiz-Herguido C, González J, López-Bigas N, Menéndez P, Dzierzak E, Espinosa L, Bigas A*. Identification of Cdca7 as a novel Notch transcriptional target involved in hematopoietic stem cell emergence. J Exp Med, 2014 . PMID: 25385755 .
  • Cases M, Briggs K, Steger-Hartmann T, Pognan F, Marc P, Kleinöder T, Schwab CH, Pastor M, Wichard J, Sanz F. The eTOX Data-Sharing Project to Advance in Silico Drug-Induced Toxicity Prediction. Int J Mol Sci, 2014; 15(11): 21136-21154. PMID: 25405742 . DOI: 10.3390/ijms151121136.

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